Results 131 to 140 of about 192,679 (274)

An effective ECOLASSO with black widow optimization for feature selection and stagewise adaptive learning rate for disease prediction

Discover Artificial Intelligence
Machine learning techniques are utilized for early detection of diseases, which can significantly enhance probabilities of positive treatment and existence.
G. Vijaya, G. Sathish Kumar, G. Uma Maheshwari, M. Karthiga, S. Hemkiran, Seyed Jalaleddin Mousavirad, Ghanshyam G. Tejani   +6 more
doaj   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

Developmentally Inspired, Mechanical–Metabolic Dual Gradient Osteochondral Constructs Bridging Regeneration and Therapeutic Screening

Advanced Science, EarlyView.
A developmentally inspired osteochondral construct integrates mechanical and metabolic dual gradients within a 3D‐printed platform. Human MSC spheroids are spatially directed to form cartilage–bone interfaces, enabling evaluation of regeneration without biochemical reagents and assessment of drug responses. This physiologically relevant, phase‐specific
Yurim Choi, Wonjun Jang, Raehui Kang, Ulziituya Batjargal, Jihyeon Song, Soojin Park, MinSeok Kim, Hyobum Cho, Junhyung Kim, Yu Shrike Zhang, Han‐Jun Kim, Junmin Lee   +11 more
wiley   +1 more source

High-accuracy lung sound classification for healthy versus unhealthy diagnosis using artificial neural network

Frontiers in Bioengineering and Biotechnology
IntroductionIn recent years, advancements in machine learning and electronic stethoscope technology have enabled high-precision recording and analysis of lung sounds, significantly enhancing pulmonary disease diagnosis.MethodsThis study presents a ...
Weiwei Zhang, Xinyu Li, Qiao Liu, Xiangyang Zheng, Yisu Ge, Xiaotian Pan, Xiaotian Pan, Yu Zhou   +7 more
doaj   +1 more source

Clinical application of the perfect closed type heart-lung machine circuit. Realization of the easy extracorporeal circulation operation.

, 1998
Naoki Momose
openalex   +2 more sources

Effects of the heart-lung machine on melatonin metabolism and mood disturbances☆ [PDF]

, 2008
Rémy Chenevard, Yves Suter, Paul Erné
openalex   +1 more source

Is it time to automate the heart lung machine? [PDF]

, 2021
John M. Toomasian
openalex   +1 more source

Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine

Advanced Science, EarlyView.
This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan, Beibei Xu, Jenna McCormack, XuHai Huang, Jingzhe Ma, Thomas Marshall, Yacong Sun, Hardeep Singh, Alyssa Fanelli, Gauri Kulkarni, Ji Hye Seo, Paige Gilbride, Bing Wei, Bo Wang, Yanyan Liu, Fei Ma, Lin Zhou, Shuyang Wang, Xiaohua Qian, Zhiyong Xie, Polina Golland, Longlong Si, Yu Shrike Zhang, Xin Xie, Haiqing Bai   +24 more
wiley   +1 more source

A dream of the heart: the life of John H. Gibbon, Jr, father of the heart-lung machine [PDF]

, 2000
James A. DeWeese
openalex   +1 more source