Results 111 to 120 of about 185,979 (321)

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

Intravenous ganciclovir prophylaxis for cytomegalovirus in heart, heart-lung, and lung transplant recipients [PDF]

, 1999
T. G. Wreghitt, Simon J. C. Abel, K. McNeil, Jayan Parameshwar, L. Sharpies, Stephen Large, J. Wallwork, Susan Stewart, N. Cary   +8 more
openalex   +1 more source

Dynamic Fibrous Hydrogels for Stem Cell Homing and In Situ Bone Regeneration

Advanced Science, EarlyView.
A dynamic fibrous hydrogel (DFH) is developed by covalent crosslinking of gelatin with tea‐derived trichomes, which integrates the structural and compositional fidelity of native extracellular matrix with photothermal and oxidative responsiveness, introducing a novel “stem cell recruits stem cell” strategy that orchestrates co‐homing of endogenous and ...
Jianmei Chen, Meiling Su, Xinyu Wu, Hongyu Wu, Haotian Wu, Pinghu Zhang, Xueying An, Zongguang Liu   +7 more
wiley   +1 more source

Stem cell therapy targeting the right ventricle in pulmonary arterial hypertension: is it a potential avenue of therapy?

Pulmonary Circulation, 2018
Pulmonary arterial hypertension (PAH) is an incurable disease characterized by an increase in pulmonary arterial pressure due to pathological changes to the pulmonary vascular bed.
Fanny Loisel, Bastien Provost, François Haddad, Julien Guihaire, Myriam Amsallem, Bojan Vrtovec, Elie Fadel, Georges Uzan, Olaf Mercier   +8 more
doaj   +1 more source

Lung transplantation in an intensive care patient with pulmonary alveolar microlithiasis - a case report [v1; ref status: indexed, http://f1000r.es/3c2]

F1000Research, 2014
Introduction: Pulmonary alveolar microlithiasis (PAM) is an autosomal recessive disease characterized by the deposition of phosphate and calcium in the alveoli. The disease progresses asymptomatically until later stages. When it becomes symptomatic, lung
Bülent Güçyetmez, Aylin Ogan, Aylin Çimet Ayyıldız, Berrin Yalçın Güder, Walter Klepetko   +4 more
doaj   +1 more source

Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

Advanced Science, EarlyView.
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang, Yiming Liam Liu, Yidi Augenstern Du, Shan−Shan Wang, Bo O. Zhou   +4 more
wiley   +1 more source

Clinical characteristics of hemodynamics and laboratory parameters of recipients during orthotopic heart transplantation

Український журнал клінічної хірургії
Objective. To study the clinical and laboratory characteristics of recipients during orthotopic heart transplantation according to intraoperative monitoring. Materials and methods.
M. M. Goncharenko
doaj   +1 more source

Impact of advanced medical therapy for the outcome of an adult patient with Eisenmenger syndrome

Respiratory Medicine Case Reports, 2017
Eisenmenger syndrome (ES) is the most severe form of pulmonary arterial hypertension (PAH) associated with congenital heart disease. It is an extremely devastating condition with a serious impact on patients' life.
Eglė Ereminienė, Marija Kinderytė, Skaidrius Miliauskas   +2 more
doaj   +1 more source

Idiopathic pulmonary fibrosis with complication of severe respiratory failure, right heart failure, and steroid induced diabetes – qualification for lung transplantation as a matter of urgency [PDF]

, 2016
Beata P. Kraśnicka-Sokół, Stanisław Laskowski, Krzysztof Kanafa, Marta Malinowska, Monika Bogulas, M Kochmański   +5 more
openalex   +1 more source

MSC Membrane‐Coated circPROSC‐siRNA Nanoparticles for Ameliorating Craniosynostosis by Inhibiting Premature Suture Ossification

Advanced Science, EarlyView.
CircPROSC promotes craniosynostosis by sponging miR‐6815‐5p, thereby activating WNT3A/β‐catenin signaling and enhancing RUNX2‐mediated osteogenesis. Targeted silencing of circPROSC with MSC membrane–coated siRNA nanoparticles (MM@Lipo/si‐circPROSC) delivered postnatally into cranial sutures attenuates premature suture closure in Twist1+/– mice ...
Zhenkun Weng, Xiu Chen, Jin Xu, Qing Yan, Jian Jiao, Qian Liu, Aihua Gu   +6 more
wiley   +1 more source