Results 131 to 140 of about 164,460 (356)
Advanced Science, EarlyView.Embelin cotargets SHP2 to disrupt the SHP2/GRB2/SOS complex, inhibiting cancer‐related signaling pathways such as MAPK, (PI3K)/AKT pathway, and XIAP to induce apoptosis signaling pathway, respectively, leading to synthetic lethality in KRAS‐mutant NSCLC cells both in vivo and in vitro.
Nai‐jie Fu +8 more
wiley +1 more source
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background Calreticulin (CRT), an endoplasmic reticulum–resident protein generally overexpressed in cancer cells, is associated with radiation resistance. CRT shows higher transacetylase activity, as shown by us earlier, in the presence of the polyphenolic acetates (like 7, 8‐diacetoxy‐4‐methylcoumarin, DAMC) and modifies the activity of a ...
Amit Verma +6 more
wiley +1 more source
World's first en bloc heart-lung transplantation using the paragonix lungguard donor preservation system. [PDF]
J Cardiothorac Surg, 2023 Neto D, Guenthart B, Shudo Y, Currie ME.
europepmc +1 more source
Epidemiology of Cryptococcosis and Cryptococcal Meningitis in a large retrospective cohort of patients after solid organ transplantation [PDF]
, 2017 Background Cryptococcosis is the third most common invasive fungal infection in solid organ transplant (SOT) recipients. There are no nationally representative data describing the incidence, risk factors, and outcomes of cryptococcosis ...
George, Ige A +3 more
core +2 more sources
Advanced Science, EarlyView.In this study, CaCO3/Mn/Cu@lip‐Apt release Mn*, Cu2+, and Ca2+ in cells. The high valence Mn ion in Mn* can effectively consume GSH, allowing more Cu2+ to participate in cuproptosis. This situation will induce the oligomerization of DLAT. The large accumulation of Ca2+ leads to intracellular calcium overload, resulting in metabolism disorders. Finally,
Shiwei Liu +7 more
wiley +1 more source
Maternal obesity and resistance to breast cancer treatments among offspring: Link to gut dysbiosis
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background About 50 000 new cases of cancer in the United States are attributed to obesity. The adverse effects of obesity on breast cancer may be most profound when affecting the early development; that is, in the womb of a pregnant obese mother.
Fabia de Oliveira Andrade +2 more
wiley +1 more source
Technical Aspects of Combined Heart-Lung Transplantation. [PDF]
J Chest Surg, 2022 Ju MH, Je HG.
europepmc +1 more source
Survival tree and meld to predict long term survival in liver transplantation waiting list [PDF]
arXiv, 2008 Background: Many authors have described MELD as a predictor of short-term mortality in the liver transplantation waiting list. However MELD score accuracy to predict long term mortality has not been statistically evaluated. Objective: The aim of this study is to analyze the MELD score as well as other variables as a predictor of long-term mortality ...
arxiv
Transplantation of the heart and both lungs: II. Experimental cardiopulmonary transplantation [PDF]
, 1969 D B Longmore +4 more
openalex +1 more source
Advanced Science, EarlyView.ROS‐activated nanohydrogels composite bilayer scaffolds are rationally designed for targted dual‐lineage repair of osteochondral defects. The as‐prepared nanohydrogel scaffolds provided 3D culture and induced dual‐lineage differentiation of BMSCs in vitro, efficiently inhibited early‐stage inflammation by rapidly releasing DS and improved cartilage and
Xiuhui Wang +14 more
wiley +1 more source