Results 51 to 60 of about 164,460 (356)

Pediatric lung transplantation: The years 1985 to 1992 and the clinical trial of FK 506 [PDF]

, 1993
The application of lung transplantation to the pediatric population was a natural extension of the success realized in our adult transplantation program, which began in 1982. Twenty pediatric patients (age range 3 to 18 years) have had heart-lung (n = 11)
Armitage, Armitage, Baldwin, Bartley P. Griffith, Billingham, Bisson, Cooper, Frederick J. Fricker, Geoffrey Kurland, Griffith, Hardesty, John M. Armitage, Keenan, Krien, Kusne, Marian Michaels, Patterson, Robert L. Hardesty, Ronald Jaffe, Rosendale, Samuel A. Yousem, Shigeki Morita, Tamaura, Thomas E. Starzl, Yousem, Zeevi, Zenati, Zenati   +27 more
core   +1 more source

Current status of liver transplantation for non‐B non‐C liver cirrhosis and hepatocellular carcinoma

Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 42-52, January 2023., 2023
Recently, the cases of LT for non‐B non‐C cirrhosis and HCC have been increasing in Japan as well as worldwide. Perioperative management of non‐B non‐C liver disease is problematic due to various risk factors, including alcohol consumption and metabolic syndrome‐related risks, such as obesity and diabetes mellitus.
Takahiro Nishio, Takashi Ito, Koichiro Hata, Kojiro Taura, Etsuro Hatano   +4 more
wiley   +1 more source

BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection

Pharmacological Research, 2022
Smooth muscle cell (SMC) loss is the characteristic feature in the pathogenesis of aortic dissection (AD), and ferroptosis is a novel iron-dependent regulated cell death driven by the excessive lipid peroxidation accumulation.
Yue Chen, Xin Yi, Bo Huo, Yi He, Xian Guo, Zihao Zhang, Xiaoxuan Zhong, Xin Feng, Ze-Min Fang, Xue-Hai Zhu, Xiang Wei, Ding-Sheng Jiang   +11 more
doaj  

A clinical trial combining donor bone marrow infusion and heart transplantation: intermediate-term results. [PDF]

, 2000
BACKGROUND: Donor chimerism (the presence of donor cells of bone marrow origin) is present for years after transplantation in recipients of solid organs. In lung recipients, chimerism is associated with a lower incidence of chronic rejection.
Fung, JJ, Griffith, BP, Hattler, BG, Kormos, RL, McCurry, KR, Pham, SM, Rao, AS, Starzl, TE, Zeevi, A   +8 more
core   +1 more source

Identification of common blood gene signatures for the diagnosis of renal and cardiac acute allograft rejection. [PDF]

, 2013
To test, whether 10 genes, diagnostic of renal allograft rejection in blood, are able to diagnose and predict cardiac allograft rejection, we analyzed 250 blood samples from heart transplant recipients with and without acute rejection (AR) and with ...
Hsieh, Szu-Chuan, Khush, Kiran, Li, Li, Luikart, Helen, Roedder, Silke, Sarwal, Minnie M, Sigdel, Tara, Valantine, Hannah, Yang, Andrew, Ying, Lihua   +9 more
core   +5 more sources

Tüdőtranszplantáció magyar betegek számára [PDF]

, 2015
When conservative treatment fails, lung transplantation often remains the only therapeutic option for patients with end stage parenchymal or vascular lung diseases.
Czebe K, Gieszer B, Lang, György, Rényi-Vámos, Ferenc István   +3 more
core   +1 more source

Immunosuppressive Drugs in Early Systemic Sclerosis and Prevention of Damage Accrual

Arthritis Care &Research, EarlyView.
Objective Organ damage in patients with systemic sclerosis (SSc) in individual organs such as the lungs may be prevented by receiving immunosuppressive drugs (ISs). A new measure of global organ damage, the Scleroderma Clinical Trials Consortium Damage Index (SCTC‐DI), has allowed us to investigate whether receiving ISs may reduce global organ damage ...
Murray Baron, Mandana Nikpour, Dylan Hansen, Susanna Proudman, Wendy Stevens, on behalf of the Australian Scleroderma Interest Group and the Canadian Scleroderma Research Group, Joanne Sahhar, Nava Ferdowsi, Kathleen Morrisroe, Laura Ross, Gene Siew Ngian, Jennifer Walker, Janet Roddy, Lauren Host, Mohammed Osman, Peter Docherty, Paul Fortin, Marvin Jacob Fritzler, Genevieve Gyger, Alena Ikic, Niall Jones, Elzbieta Kaminska, Maggie Larche, Sophie Ligier, Ada Man, Ariel Masetto, Janet Pope, David Robinson, Tatiana Sofia Rodriguez‐Reyna, Mianbo Wang   +29 more
wiley   +1 more source

Lovo‐cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB‐206 study

American Journal of Hematology, Volume 98, Issue 1, Page 11-22, January 2023., 2023
Treatment process evolution. *The target TNC for BMH was ≥6 × 108/kg per patient. The Group B1 patient received lovo‐cel produced using both the original and refined manufacturing process, and the Group B2 patient received lovo‐cel produced using only the refined manufacturing process.
Julie Kanter, Alexis A. Thompson, Francis J. Pierciey Jr, Matthew Hsieh, Naoya Uchida, Philippe Leboulch, Manfred Schmidt, Melissa Bonner, Ruiting Guo, Alex Miller, Jean‐Antoine Ribeil, David Davidson, Mohammed Asmal, Mark C. Walters, John F. Tisdale   +14 more
wiley   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

MicroRNAs Implicated in Dysregulation of Gene Expression Following Human Lung Transplantation [PDF]

Transl Respir Med. 2013; 1: 12, 2013
Lung transplantation remains the only viable treatment option for the majority of patients with advanced lung diseases. However, 5-year post-transplant survival rates remain low primarily secondary to chronic rejection. Novel insights from global gene expression profiles may provide molecular phenotypes and therapeutic targets to improve outcomes after
arxiv   +1 more source