Results 61 to 70 of about 137,114 (301)

Lung and heart-lung transplantation

Cardiology in the Young, 2009
I NCREASED UNDERSTANDING AND AWARENESS OF congenital cardiac disease has allowed early identification of these children. Advances in surgical techniques, anesthesia, and medical treatment have rendered the majority of forms of congenital cardiac defects treatable.
Date, Hiroshi, Sweet, Stuart C
openaire   +4 more sources

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part I: Epidemiology, assessment of extrapulmonary conditions, candidate evaluation, selection criteria, and pathology statements [PDF]

, 2021
Patients with connective tissue disease (CTD) and advanced lung disease are often considered suboptimal candidates for lung transplantation (LTx) due to their underlying medical complexity and potential surgical risk.
Snyder, Laurie D., Crespo, Maria M., Farver, Carol, Meyer, Keith C., Bhorade, Sangeeta, Lease, Erika D., Willie, Keith, Shtraichman, Osnat, Bemiss, Brad, Sole, Amparo, Le Pavec, Jérôme, Kaza, Vaidehi, Patterson, Caroline M., Howsare, Molly, Strah, Heather, Holm, Are, Berry, Gerald J., Murray, Michelle, Nair, Arun, Venado, Aida E., Dilling, Daniel F., Wassilew, Katharina, Gries, Cynthia, Budev, Marie, Goldberg, Hilary, Sandorfi, Nora, Tokman, Sofya, McWilliams, Tanya, Shah, Rupal J., Cifrian, Jose M., Salgado, Juan   +30 more
core   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, Accepted Article.
Objective VEXAS syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures. A VEXAS‐specific disease activity index (DAI) is an essential tool for reliably capturing changes in disease ...
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

Three‐Dimensional Biomimetic Aerogel Conduits with Electro‐Ionic‐Immune Coupling Reverse the Pathological Cascade of Spinal Cord Injury

Advanced Functional Materials, EarlyView.
A biomimetic aerogel conduit was engineered from a nanofiber of gelatin/poly(l‐lactic acid) doped with polypyrrole nanoparticles, integrated with tannic acid and Mg2+. This “electro‐ionic‐immune” strategy mimicked spinal cord properties, reduced calcium overload, inflammation, oxidative damage, promoted neural stem cell differentiation, suppressed ...
Qingxiang Liu, Xin Yu, Jingtong Li, Chunyang Zheng, Yukang Zhang, Mingyu Jia, Tan Tian, Weiwei Zheng, Pinghui Zhou, Yingji Mao   +9 more
wiley   +1 more source

Primary Graft Dysfunction Grade 3 following Pediatric Lung Transplantation is Associated with Chronic Lung Allograft Dysfunction [PDF]

, 2023
Background: Severe primary graft dysfunction (PGD) is associated with the development of bronchiolitis obliterans syndrome (BOS), the most common form of chronic lung allograft dysfunction (CLAD), in adults.
Cheng, Pi Chun, Yehya, Nadir, Josephson, Maureen B., Kawut, Steven M., Goldfarb, Samuel B., Berg, Robert A., Himebauch, Adam S., Wong, Wai, Harhay, Michael O., Maeda, Katsuhide, Johnson, Brandy   +10 more
core   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Risk factors for Chagas` disease reactivation after heart transplantation [PDF]

, 2008
Background: Chagas` disease is the illness caused by the protozoan Trypanosoma cruzi and it is still endemic in Latin America. Heart transplantation is a therapeutic option for patients with end-stage Chagas` cardiomyopathy.
BOCCHI, Edimar A., BACAL, Fernando, AMATO NETO, Vicente, STRABELLI, Tania Mara V., CAMPOS, Silvia V., SILVA, Christiano P., STOLF, Noedir Antonio G.   +6 more
core   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Orthotopic Heart Transplantation in a Child with Severe Heart Failure and Chylous Ascites [PDF]

, 2008
We report a case of a heart transplantation in a 12-year-old girl 9 years after extensive lung resection and adjuvant chemo- and radiotherapy for intra-thoracic embryonic rhabdomyosarcoma.
HSU, RON-BIN;WU, MEI-HWAN;WANG, JOU-KOU;WANG, SHOEI-SHEN;CHU, SHU-HSUN, 許榮彬;吳美環;王主科;王水深;朱樹勳   +1 more
core