Results 91 to 100 of about 16,119 (209)

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

Sympathetic Dysautonomia in Heart Failure by 123I-MIBG: comparison between Chagasic, non-Chagasic and heart transplant patients

Arquivos Brasileiros de Cardiologia, 2018
Background: Heart failure (HF) is a severe public health problem because of its high morbidity and mortality and elevated costs, thus requiring better understanding of its course.
Viviane Santuari Parisotto Marino, Sandra Monetti Dumont, Luciene das Graças Mota, Daniela de Souza Braga, Stephanie Saliba de Freitas, Maria da Consolação Vieira Moreira   +5 more
doaj   +1 more source

Efficacy of Olfactory and Pareidolia Tests Compared With That of Indicative Biomarkers in Diagnosis of Dementia With Lewy Bodies

Frontiers in Neurology, 2020
Purpose: Although olfactory decline and visual hallucinations are useful in distinguishing dementia with Lewy bodies (DLB) from Alzheimer's disease (AD) in a clinical setting, neither is easy to evaluate objectively. The pareidolia test is used to assess
Yuta Inagawa, Hidekazu Kanetaka, Akito Tsugawa, Shu Sakurai, Shuntaro Serisawa, Soichiro Shimizu, Hirofumi Sakurai, Haruo Hanyu   +7 more
doaj   +1 more source

The Thoracic Lymphatic Vasculature: Interorgan Strategies to Achieve an Optimal Tissue Function

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
In the thorax, organ‐specific features such as stomata and submesothelial lacunae, pulmonary perivascular and peribronchial vessels, and subepicardial lymphatic network allow the thoracic lymphatics to perform as a dynamically regulated system able to exploit local mechanical forces and tissue‐specific architecture to maintain fluid and solute ...
Daniela Negrini, Eleonora Solari, Cristiana Marcozzi, Andrea Moriondo   +3 more
wiley   +1 more source

Motor and Cognitive Outcome After Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson's Disease Harboring GBA1 Variant

Movement Disorders Clinical Practice, Volume 13, Issue 4, Page 973-984, April 2026.
Abstract Background Deep brain stimulation (DBS) is effective for Parkinson's disease (PD); however, its efficacy varies with genetic background, such as the GBA1 variant—the causative gene of Gaucher disease—associated with increased PD risk and cognitive decline after subthalamic nucleus (STN)‐DBS.
Hikaru Kamo, Genko Oyama, Mai Shimizu, Haruka Takeshige‐Amano, Takashi Ogawa, Wataru Sako, Noriko Nishikawa, Taku Hatano, Yuanzhe Li, Hiroyo Yoshino, Manabu Funayama, Masanobu Ito, Hirokazu Iwamuro, Atsushi Umemura, Nobutaka Hattori   +14 more
wiley   +1 more source

Value of multi-parameter 123I-MIBG scintigraphy in the differential diagnosis of Parkinson’s disease

EJNMMI Research
Background 123I-MIBG scintigraphy plays a significant role in diagnosing Parkinson's disease (PD), with most studies primarily targeting cardiac uptake and relying on traditional ratio-based parameters for assessment.
Teng Xue, Ying Cui, Ying Kan, Guanyun Wang, Jigang Yang   +4 more
doaj   +1 more source

Cardiac Sympathetic Activity differentiates Idiopathic and Symptomatic Rapid Eye Movement Sleep Behaviour Disorder

Scientific Reports, 2018
The pathophysiology of rapid eye movement sleep behavior disorder (RBD) associated with narcolepsy type 1 (NT1) is still poorly understood, potentially distinct from idiopathic RBD (iRBD), but may share affected common pathways.
Lucie Barateau, Isabelle Jaussent, Régis Lopez, Elisa Evangelista, Sofiene Chenini, Meriem Benkiran, Denis Mariano-Goulart, Yves Dauvilliers   +7 more
doaj   +1 more source

The helpful support of veno‐arterial extracorporeal membrane oxygenation to treat an exceptional systemic‐to‐pulmonary venous shunt: A case report

Physiological Reports, Volume 14, Issue 7, April 2026.
Abstract Systemic‐to‐pulmonary venous shunting is a rare cause of refractory hypoxemia. Its prompt recognition is crucial, as management requires not only etiological treatment but also the restoration of physiological venous return. We report the case of a 40‐year‐old man presenting with dyspnea, cervicothoracic edema, and hypoxemia.
Ludovic van Delden, Matis Grundheber, Carole Looyens, Benjamin Assouline, Matthieu Papillard, Raphael Giraud, Karim Bendjelid   +6 more
wiley   +1 more source

Diagnostic Efficacy of ¹²³Iodo-Metaiodobenzylguanidine SPECT/CT in Cardiac vs. Neurological Diseases: A Comparative Study of Arrhythmogenic Right Ventricular Cardiomyopathy and α-Synucleinopathies

Diagnostics
Background/Objectives: 123Iodo-metaiodobenzylguanidine single photon emission computed tomography/computed tomography (123I-MIBG SPECT/CT) is used to evaluate the cardiac sympathetic nervous system in cardiac diseases such as arrhythmogenic right ...
Johannes M. Hagen, Maximilian Scheifele, Mathias J. Zacherl, Sabrina Katzdobler, Alexander Bernhardt, Matthias Brendel, Johannes Levin, Günter U. Höglinger, Sebastian Clauß, Stefan Kääb, Andrei Todica, Guido Boening, Maximilian Fischer   +12 more
doaj   +1 more source

Variations in 123I-metaiodobenzylguanidine (MIBG) late heart mediastinal ratios in chronic heart failure: a need for standardisation and validation [PDF]

, 2007
BACKGROUND: There is lack of validation and standardisation of acquisition parameters for myocardial (123)I-metaiodobenzylguanidine (MIBG). This lack of standardisation hampers large scale implementation of (123)I-MIBG parameters in the evaluation of ...
Hein J. Verberne, Jan B. A. Habraken, Berthe L. F. van Eck-Smit, Denis Agostini, Arnold F. Jacobson, JC Sisson, RC Kline, P Merlet, P Merlet, M Momose, A Cohen-Solal, T Wakabayashi, S Kasama, T Yamada, M Kyuma, T Nakata, R Arora, M Paul, HJ Verberne, D Agostini, M Suwa, M Estorch, FI Parthenakis, GA Lanza, T Wichter, Y Inoue, AA Dobbeleir, GA Somsen, EA Byrne, A Colosimo, N Craft, MD Esler, BA Kingwell, T Laitinen, H Tsuji, K Shimada, MR Cowie, S Iwase, O Randall, GA Somsen, M Estorch, P Merlet, D Agostini, JJ Visser, KE Britton   +44 more
core   +1 more source