Results 91 to 100 of about 532,909 (177)

Cell Death Response to DNA Damage. [PDF]

, 2019
The cell death response to DNA damage is discussed in this Perspectives piece with cancer as the backdrop because DNA damaging agents (DDA) are widely used to treat cancer.
Wang, Jean YJ
core   +1 more source

Galectin-12 in Cellular Differentiation, Apoptosis and Polarization. [PDF]

, 2018
Galectin-12 is a member of a family of mammalian lectins characterized by their affinity for β-galactosides and consensus amino acid sequences. The protein structure consists of a single polypeptide chain containing two carbohydrate-recognition domains ...
Liu, Fu-Tong, Wan, Lei, Yang, Ri-Yao
core   +2 more sources

Early Outcomes of Out-of-Hospital Cardiac Arrest after Early Defibrillation: a 24 Months Retrospective Analysis [PDF]

, 2006
Introduction: Cardiovascular disease remains the most common cause of death in the United States and most other Western nations. Among these deaths, sudden, out-of-hospital cardiac arrest claims approximately 1000 lives each day in the United States ...
Barbara Severgnini, Enrico Maria Greco, Paolo Terranova, Paolo Valli, Simonetta Dell'Orto   +4 more
core   +1 more source

Cardiorespiratory depression from brainstem seizure activity in freely moving rats

Neurobiology of Disease, 2020
Cardiorespiratory dysfunction during or after seizures may contribute to sudden unexpected death in epilepsy. Disruption of lower brainstem cardiorespiratory systems by seizures is postulated to impair respiratory and cardiac function.
Wanida Lertwittayanon, Orrin Devinsky, Peter L. Carlen   +2 more
doaj  

Combinatorial genetic replenishments in myocardial and outflow tract tissues restore heart function in tnnt2 mutant zebrafish

Biology Open, 2019
Cardiac muscle troponin T (Tnnt2) mediates muscle contraction in response to calcium ion dynamics, and Tnnt2 mutations are associated with multiple types of cardiomyopathy.
Lian Liu, Fei Fei, Ranran Zhang, Fang Wu, Qian Yang, Feng Wang, Shaoyang Sun, Hui Zhao, Qiang Li, Lei Wang, Youhua Wang, Yonghao Gui, Xu Wang   +12 more
doaj   +1 more source

Surgical Correction of Infundibular Muscular Ventricular Septal Defect in a Cat: A Case Report

Animals
Ventricular septal defects (VSDs) can lead to congestive heart failure and pulmonary hypertension, particularly in patients with large shunts. However, no surgical treatment for feline VSD has been reported.
Takuma Aoki, Tomomi Terakado, Yao Jingya, Kentaro Iwasaki, Hayato Shimoda, Naoyuki Fukamachi, Takashi Miyamoto   +6 more
doaj   +1 more source

Akt1-mediated CPR cooling protection targets regulators of metabolism, inflammation and contractile function in mouse cardiac arrest.

PLoS ONE, 2019
Therapeutic hypothermia initiated during cardiopulmonary resuscitation (CPR) in pre-clinical studies appears to be highly protective against sudden cardiac arrest injury.
Jing Li, Xiangdong Zhu, Huashan Wang, Chunpei Lee, Sy-Jou Chen, Yuanyu Qian, Mei Han, Ryan Bunney, David G Beiser, Terry L Vanden Hoek   +9 more
doaj   +1 more source

Inter-rater reliability of post-arrest cerebral performance category (CPC) scores. [PDF]

, 2016
PURPOSE: Cerebral Performance Category (CPC) scores are often an outcome measure for post-arrest neurologic function, collected worldwide to compare performance, evaluate therapies, and formulate recommendations.
Abella, Benjamin S., Cinousis, Marisa J., Gaieski, David F., Grossestreuer, Anne V., Leary, Marion, Perman, Sarah M., Sheak, Kelsey R., Wiebe, Douglas J.   +7 more
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Acute coronary syndrome in diclofenac sodium-induced type I hypersensitivity reaction : Kounis syndrome [PDF]

, 2007
Drug-induced type I hypersensitivity reactions are frequent. Sometimes, acute coronary syndrome (ACS) can be registered in such patients, which may have a serious impact on the course and management of the allergic reaction.
Gluvic, Zoran M., Jankovic-Gavrilovic, Jelena, Panic, Milos, Putnikovic, Biljana, Rasic-Milutinovic, Zorica, Stojkovic, Aleksandra   +5 more
core  

The association between hemoglobin concentration and neurologic outcome after cardiac arrest. [PDF]

, 2016
PURPOSE: The purpose of the study is to determine the association between hemoglobin concentration (Hgb) and neurologic outcome in postarrest patients. METHODS: We conducted a retrospective cohort study using the Penn Alliance for Therapeutic Hypothermia
Dodampahala, Kalani, Gaieski, David F., Goyal, Munish, Grossestreuer, Anne V., Johnson, Nicholas J., Perman, Sarah M., Rosselot, Babette   +6 more
core   +1 more source