Results 41 to 50 of about 2,889,732 (344)
Circulation, 2015 The American Heart Association (AHA) commends the recently released Institute of Medicine (IOM) report, Strategies to Improve Cardiac Arrest Survival: A Time to Act (2015).
R. Neumar +10 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Wearable Device to Detect Cardiac Arrest [PDF]
, 2017 Cardiac arrest is one of the leading causes of death globally and is unwitnessed in most cases. This begs the question: how can anyone know that an individual is experiencing cardiac arrest if no one is around to see it?
Al Gumaei, Ashraf +2 more
core +2 more sources
Post-TTM Rebound Pyrexia after Ischemia-Reperfusion Injury Results in Sterile Inflammation and Apoptosis in Cardiomyocytes [PDF]
, 2019 Introduction. Fever is frequently observed after acute ischemic events and is associated with poor outcome and higher mortality. Targeted temperature management (TTM) is recommended for neuroprotection in comatose cardiac arrest survivors, but pyrexia ...
Berger, Felix +6 more
core +1 more source
Oxidative Medicine and Cellular Longevity, 2015 Cardiac arrest induces whole-body ischemia, which causes damage to multiple organs. Understanding how each organ responds to ischemia/reperfusion is important to develop better resuscitation strategies. Because direct measurement of organ function is not
Junhwan Kim +7 more
semanticscholar +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
Recovery of hypoxic neonatal hearts after cardioplegic arrest [PDF]
Cardiovascular Research, 1993 Surgery for repair of congenital heart defects in the infant may be affected by hypoxia associated with the defect. The effects of chronic hypoxia on systemic ventricular function are not well characterised and few studies have considered myocardial preservation in the hypoxic neonatal heart.
Linda J. Veit +2 more
openaire +6 more sources
Targeted temperature management in emergency medicine: current perspectives [PDF]
, 2015 Landmark trials in 2002 showed that therapeutic hypothermia (TH) after out-of-hospital cardiac arrest due to ventricular tachycardia or ventricular fibrillation resulted in improved likelihood of good neurologic recovery compared to standard care without
Ellender, Timothy J., Hunter, Benton R.
core +1 more source
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
FEBS Open Bio, EarlyView.Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh +2 more
wiley +1 more source
A method of producing cardiac arrest in the dog. [PDF]
, 1953 Thesis (M.A.)--Boston ...
Ryan, Martin Lester
core +1 more source