Results 111 to 120 of about 5,481,660 (373)

Bloqueio Aurículo-Ventricular Completo Congénito. Caso Clínico e Revisão da Literatura [PDF]

open access: yes, 2015
Introduction: Congenital complete atrioventricular block (AVB) without cardiac malformation is a rare and potentially fatal condition. In most cases it is associated with maternal systemic lupus erythematosus through transplacental passage of antibodies ...
Borges, A   +3 more
core  

Impaired endocytosis of the ion channel TRPM4 is associated with human progressive familial heart block type I.

open access: yesJournal of Clinical Investigation, 2009
Progressive familial heart block type I (PFHBI) is a progressive cardiac bundle branch disease in the His-Purkinje system that exhibits autosomal-dominant inheritance.
M. Kruse   +9 more
semanticscholar   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach   +11 more
wiley   +1 more source

Cardiogenic shock with 1° heart block after organophosphorus poisoning: A case report and review of cardiac complication in organophosphorus poisoning

open access: yesCHRISMED Journal of Health and Research, 2015
Organophosphorus (OP) compounds have been widely used as pesticide in India. Because of wide use and easy availability, it is the most common poisoning. OP compound poisoning can lead to cardiac complications.
Manoj Lakhotia   +4 more
doaj   +1 more source

Blocking transport resonances via Kondo entanglement in quantum dots [PDF]

open access: yes, 2016
Many-body entanglement is at the heart of the Kondo effect, which has its hallmark in quantum dots as a zero-bias conductance peak at low temperatures. It signals the emergence of a conducting singlet state formed by a localized dot degree of freedom and
Cleuziou, J. -P.   +7 more
core   +3 more sources

OBSERVATIONS ON SINO-AURICULAR HEART BLOCK

open access: yes
Heart block is ordinarily understood to be a condition in which there is impairment in the conduction of impulses from auricles to ventricles. The first stage of this process is represented by a mere delay in the conduction time recognized by an increase
S. A. Levine
semanticscholar   +1 more source

The Comparative Effectiveness and Tolerability of Sphingosine‐1‐Phosphate Receptor Modulators in Patients With Multiple Sclerosis: A Network Meta‐Analysis of Randomized Controlled Trials

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad   +8 more
wiley   +1 more source

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont   +4 more
wiley   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry   +2 more
wiley   +1 more source

Dual Chamber Pacemaker Implant in Coronary Sinus Leading to Several Complications

open access: yesDiagnostics
Permanent pacemaker implantation is a low-risk procedure. However, complications may occur at a rate of around 4–8%. We present a case where initial implantation resulted in complications that could have been avoided by meticulous assessment of lead ...
Nancy Wassef   +5 more
doaj   +1 more source

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