Differential Effects of Vagal Activation on the Sinus and Atrioventricular Nodes
Vagal activation usually affects both sinus and atrioventricular (AV) nodes, manifesting as sinus slowing accompanied by varying degrees of AV block. AV block accompanying sinus acceleration as during treadmill testing is usually considered pathologic ...
Lauren D. Suggs, MD +2 more
doaj +1 more source
Different Impact of Beta-Blockers on Long-Term Mortality in Heart Failure Patients with and without Chronic Obstructive Pulmonary Disease [PDF]
Satoshi Higuchi +8 more
openalex +1 more source
Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide [PDF]
Background: The sulfonylurea glibenclamide (Glib) abolishes the cardioprotective effect of ischemic preconditioning (IP), presumably by inhibiting mitochondrial KATP channel opening in myocytes. Glimepiride (Glim) is a new sulfonylurea reported to affect
Baxter, G.F. +5 more
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A Distance Map Regularized CNN for Cardiac Cine MR Image Segmentation
Cardiac image segmentation is a critical process for generating personalized models of the heart and for quantifying cardiac performance parameters. Several convolutional neural network (CNN) architectures have been proposed to segment the heart chambers
Dangi, Shusil +2 more
core +1 more source
Ventricular arrhythmias in young competitive athletes: Prevalence, determinants, and underlying substrate [PDF]
Whether ventricular arrhythmias (VAs) represent a feature of the adaptive changes of the athlete's heart remains elusive. We aimed to assess the prevalence, determinants, and underlying substrates of VAs in young competitive athletes.Background--Whether ...
Badano, Luigi Paolo +19 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Sinus of Valsalva Aneurysm Dissecting into Interventricular Septum Compressing RVOT [PDF]
Aneurysm of sinus of valsalva is a rare disorder. Rupture of sinus of valsalva into the right atria, right ventricle and the left ventricle is more commonly seen.
Nishu Raj +3 more
doaj +1 more source
Neonatal lupus with atypical cardiac and cutaneous manifestation [PDF]
Neonatal lupus erythematosus is a rare, passively acquired autoimmune disease, caused by maternal autoantibodies. The most common manifestations are skin rash and congenital heart block. Cutaneous manifestations may be present at birth, but often develop
Mimoso, G +3 more
core +1 more source
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Progressive familial heart block, two types [PDF]
CITATION: Brink A. J. & Torrington, M. 1977. Progressive familial heart block, two types. South African Medical Journal, 52(2):53-59.The original publication is available at http://www.samj.org.zaTwo types of heart block which occur extensively in ...
Brink A. J., Torrington, M.
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