Results 131 to 140 of about 20,033,761 (330)

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

PHYSIOLOGICAL STIMULATION OF THE HEART – HISTORY AND THE PRESENT

Proceedings of the Shevchenko Scientific Society: Medical Sciences
The possibility of electrical stimulation of the heart has fascinated researchers and doctors since the Age of Enlightenment until the 21st century.
Оleksiy Myshakivskyy, Marta Voytsekhivska, Volodymyr Pavliuk   +2 more
doaj   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Induction and patterning of the cardiac conduction system [PDF]

, 2002
The cardiac conduction system (CCS) is the component of the heart that initiates and maintains a rhythmic heartbeat. As the embryonic heart forms, the CCS must continue to develop and mature in a coordinated manner to ensure that proper pace making ...
Gourdie, R.G., Mikawa, T., Pennisi, D.J., Fishman, G.I., Rentschler, S.   +4 more
core  

Atrioventricular conduction versus heart size from mouse to whale

, 1985
In normal sinus rhythm, the atrioventricular (AV) conduction system introduces an appropriate delay between atrial and ventricular excitation and contraction. This delay, the AV or PR interval, increases with the size of the animal and, thus,of the heart.
Frits L. Meijler, Meijler, F.L.
core   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Cardiac conduction system involvement in metastatic pancreatic ductal adenocarcinoma [PDF]

, 2005
While almost all malignant tumors are occasionally found to have metastasized to the heart, the involvement of the heart is not common and is poorly studied.
L. Matturri, G.Ottaviani
core   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Understanding the heritability of heart rhythm and conduction disorders

, 2019
The electrocardiogram (ECG) is a tool to obtain evidence for arrhythmias, which are related with cardiac conduction system abnormalities, myocardial ischemias and cardiac response to drugs.
Silva Aldana, Claudia Tamar
core   +1 more source

Seventy Seconds of Asystole

JACC: Case Reports
Background: Conduction system disturbance is a leading complication of transcatheter aortic valve replacement (TAVR). Conventional predictors of post-TAVR pacing include preexisting right bundle branch block, new left bundle branch block, and annular ...
Chaitanya L. Malladi, MD, Benjamin U. Hoffman, MD, PhD, Gary Ma, MD, Daniel Kim, MD, MS, Ryan Reeves, MD, Ori Ben-Yehuda, MD, Ehtisham Mahmud, MD, Kurt S. Hoffmayer, MD, PharmD, Jonathan C. Hsu, MD, MAS, Frederick T. Han, MD   +9 more
doaj   +1 more source