Results 111 to 120 of about 94,373 (304)

Pocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system

Biology Open, 2013
Summary During development, the ventricular conduction system (VCS) arises from the trabecular or spongy myocardium. VCS and trabecular myocytes proliferate at a significantly slower rate than compact zone myocardial cells, establishing a transmural cell
David S. Park, Rose O. Tompkins, Fangyu Liu, Jie Zhang, Colin K. L. Phoon, Jiri Zavadil, Glenn I. Fishman   +6 more
doaj   +1 more source

Identification and functional characterization of cardiac pacemaker cells in zebrafish.

PLoS ONE, 2012
In the mammalian heart a conduction system of nodes and conducting cells generates and transduces the electrical signals evoking myocardial contractions. Specialized pacemaker cells initiating and controlling cardiac contraction rhythmicity are localized
Federico Tessadori, Jan Hendrik van Weerd, Silja B Burkhard, Arie O Verkerk, Emma de Pater, Bastiaan J Boukens, Aryan Vink, Vincent M Christoffels, Jeroen Bakkers   +8 more
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Retrograde Conduction in Complete Heart Block* [PDF]

, 1966
In complete heart block, absolute independence between atrial and ventricular activity does not always occur. Several mechanisms may be postu-lated to explain this phenomenon.
Cesar Castillo, Philip Samet
core  

Derivation of the bidomain equations for a beating heart with a general microstructure [PDF]

, 2011
A novel multiple scales method is formulated that can be applied to problems which have an almost periodic microstructure not in Cartesian coordinates but in a general curvilinear coordinate system.
Chapman, Stephen, S. J. Chapman, Richardson, Giles, Richardson, G, Chapman, SJ, Chapman, S.J., G. Richardson   +6 more
core   +1 more source

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source

Cardiac conduction system regeneration prevents arrhythmias after myocardial infarction [PDF]

Arrhythmias are a hallmark of myocardial infarction (MI) and increase patient mortality. How insult to the cardiac conduction system causes arrhythmias following MI is poorly understood.
Rodriguez, Claudio Cortes, Berg, Lucas Arantes, Rodriguez, Blanca, Camps, Julia, Riebel, Leto Luana, Sayers, Judy R., de Villiers, Carla, Weinberger, Michael, Sun, Xin, Sigal, Sarah, Riley, Paul R., Martinez-Navarro, Hector, Sauka-Spengler, Tatjana, Herring, Neil   +13 more
core   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source