Results 131 to 140 of about 14,117,834 (409)

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont, Adam Deardorff, Murad Nawaz, Andrew A. Voss, Mark M. Rich   +4 more
wiley   +1 more source

A Nomogram utilizing ECG P-wave parameters to predict recurrence risk following catheter ablation in paroxysmal atrial fibrillation

Journal of Cardiothoracic Surgery
Highlights Abnormal changes in P-wave parameters indicative of atrial electrical remodeling often manifest earlier than changes in other indicators reflecting atrial structural remodeling in paroxysmal atrial fibrillation. Preoperative absolute values of
Li-juan Yu, Xue-Hai Chen, Zhe Xu, Ke-Zeng Gong, Fei-Long Zhang   +4 more
doaj   +1 more source

2021 ESC/EACTS Guidelines for the management of valvular heart disease.

European Heart Journal, 2021
A. Vahanian, F. Beyersdorf, F. Praz, M. Milojevic, S. Baldus, J. Bauersachs, D. Capodanno, L. Conradi, M. de Bonis, R. de Paulis, V. Delgado, N. Freemantle, M. Gilard, K. Haugaa, A. Jeppsson, P. Jüni, L. Pierard, B. Prendergast, J. R. Sádaba, C. Tribouilloy, W. Wojakowski, Franz‐Josef Neumann, Pat A Myers, M. Abdelhamid, S. Achenbach, R. Asteggiano, F. Barili, M. Borger, T. Carrel, J. Collet, Dan Foldager, G. Habib, C. Hassager, A. Irs, B. Iung, M. Jahangiri, H. Katus, Konstantinos C. Koskinas, S. Massberg, Christian Mueller, J. Nielsen, P. Pibarot, A. Rakisheva, M. Roffi, A. Rubboli, E. Shlyakhto, M. Siepe, M. Sitges, L. Sondergaard, M. Sousa‐Uva, G. Tarantini, J. Zamorano   +51 more
semanticscholar   +1 more source

Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies

Heart, 2016
Background The influence of social relationships on morbidity is widely accepted, but the size of the risk to cardiovascular health is unclear. Objective We undertook a systematic review and meta-analysis to investigate the association between loneliness
Nicole K Valtorta, M. Kanaan, S. Gilbody, S. Ronzi, B. Hanratty   +4 more
semanticscholar   +1 more source

Association of the ICH Score With Withdrawal of Life‐Sustaining Treatment Over a 10‐Year Period

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The intracerebral hemorrhage (ICH) score was developed to enhance provider communication and facilitate early severity assessment. We examined the association of the ICH score with mortality and withdrawal of life‐sustaining treatment (WLST) in a large, multicenter stroke registry, and evaluated temporal trends in these associations.
Nina Massad, Lili Zhou, Brian Manolovitz, Negar Asdaghi, Hannah Gardener, Hao Ying, Carolina M. Gutierrez, Angus Jameson, David Rose, Mohan Kottapally, Amedeo Merenda, Kristine O'Phelan, Sebastian Koch, Jose G. Romano, Tatjana Rundek, Ayham Alkhachroum   +15 more
wiley   +1 more source

PGAM5 expression and macrophage signatures in non-small cell lung cancer associated with chronic obstructive pulmonary disease (COPD)

BMC Cancer, 2018
Background COPD patients are at increased risk of developing non-small cell lung carcinoma that has a worse prognosis. Oxidative stress contributes to carcinogenesis and is increased in COPD patients due to mitochondrial dysfunction.
F. Ng Kee Kwong, A. G. Nicholson, S. Pavlidis, I. M. Adcock, K. F. Chung   +4 more
doaj   +1 more source

Structural Heart Disease?

Journal of the American College of Cardiology, 2014
![Figure][1] My last Editor's Page, prior to the annual Highlights of the Year in JACC paper, was devoted to a consideration of the definition of translational research. Specifically, I wondered at the imprecision of the definition and the fact that it meant different things to ...
openaire   +3 more sources

Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay, E. Vichayanrat, F. Bremner, F. Valerio, R. Mackenzie, G. Chiaro, G. Ingle, P. McNamara, L. Watson, J. N. Panicker, M. P. Lunn, C. Mathias, V. Iodice   +12 more
wiley   +1 more source

Coronavirus disease 2019 in patients with Fontan circulation

International Journal of Cardiology Congenital Heart Disease, 2021
Flavia Fusco, Giancarlo Scognamiglio, Assunta Merola, Michela Palma, Anna Correra, Nunzia Borrelli, Rosaria Barracano, Nicola Grimaldi, Diego Colonna, Emanuele Romeo, Berardo Sarubbi   +10 more
doaj   +1 more source

Large-scale discovery of enhancers from human heart tissue. [PDF]

, 2011
Development and function of the human heart depend on the dynamic control of tissue-specific gene expression by distant-acting transcriptional enhancers.
Afzal, Veena, Akiyama, Jennifer A, Black, Brian L, Blow, Matthew J, Bristow, James, Holt, Amy, Jensen, Brian C, Kaplan, Tommy, May, Dalit, McCulley, David J, Pennacchio, Len A, Plajzer-Frick, Ingrid, Rubin, Edward M, Shoukry, Malak, Simpson, Paul C, Visel, Axel, Wright, Crystal   +16 more
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