Results 41 to 50 of about 59,843 (260)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The impact of demographic and risk factor changes on coronary heart disease deaths in Beijing, 1999-2010.

, 2009
BACKGROUND: Recent, dramatic increases in coronary heart disease (CHD) mortality in China can be mostly explained by adverse changes in major cardiovascular risk factors.
Wang, W, Zeng, Z, Jing Liu, Zhao, D, Capewell, S, Jun Cheng, Critchley, JA, Julia Alison Critchley, Zeng Zhechun, Simon Capewell, Zhechun Zeng, Wang Wei, Sun, J, Jiayi Sun, Cheng, J, Capewell Simon, Liu, J, Liu Jing, Cheng Jun, Dong Zhao, Sun Jiayi, Critchley Julia, Zhao Dong, Wei Wang   +23 more
core   +1 more source

Identification of Effective Factors and Prediction of Ischemic Heart Disease Using Machine Learning Methods and Data from the Yazd Health Study (YaHS) [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Ischemic heart diseases are one of the most common diseases that cause high mortality worldwide. This article has identified various factors affecting heart disease and identified susceptible people using various machine learning methods ...
Jamal Zarepour Ahmadabadi, Fatemeh Zare Mehrjardi, Mahdieh Ghanbary, Masoud Mirzaei   +3 more
doaj  

Stroke and systemic embolism in adult congenital heart disease

International Journal of Cardiology Congenital Heart Disease, 2023
Despite striking improvement in survival of patients with congenital heart disease (CHD), the risk of long-term complications remains high. Stroke and systemic embolism are common and potentially devastating complications that significantly affect ...
Katja Prokšelj
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Coronary heart disease and risk factors in elderly population

Кардиоваскулярная терапия и профилактика, 2016
The treatment and prevention events against cardiovascular diseases have changed the age population structure. As by forecast, in RF the part of population older than economically active age will increase to 29,1% by the year 2030, hence increasing ...
A. E. Imaeva, E. M. Tuaeva, S. A. Shalnova, N. V. Kiseleva   +3 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Lung Function and Risk of Type 2 Diabetes and Fatal and Nonfatal Major Coronary Heart Disease Events: Possible Associations With Inflammation [PDF]

, 2010
OBJECTIVE - We prospectively examined the relationship between lung function and risk of type-2 diabetes and fatal and nonfatal coronary heart disease (CHD) events and investigated the hypothesis that inflammation may underlie these associations ...
Lowe, G.D., Lowe, GD, Wannamethee, S. G., Whincup, PH, Sattar, N, Sattar, N., Thomas, MC, Peter H. Whincup, Rumley, A., Ann Rumley, Naveed Sattar, A. Gerald Shaper, S. Goya Wannamethee, Shaper, AG, Gordon D. Lowe, Rumley, A, Whincup, P. H., Mary C. Thomas, Wannamethee, SG, Shaper, A. G., Thomas, M. C.   +20 more
core   +1 more source

CARACTERIZACIÓN DE LOS FACTORES DE RIESGO VASCULAR EN PACIENTES ADULTOS / Characterization of vascular risk factors in adult patients [PDF]

CorSalud, 2013
Resumen: Introducción: La elevada prevalencia de factores de riesgo vascular en la población y su relación con el desarrollo de la cardiopatía isquémica representan un problema de salud pública. Objetivo: Caracterizar estos factores en adultos.
Estrella M. Hernández Hurtado, Yannelis Rodríguez Valido, Valentina Carpio García, Isis Yera Alós, Liset Valdés Manresa, Nercy O. Díaz Águila, Orestes Díaz Castro, Orestes Díaz Águila   +7 more
doaj  

Relationship of Neighborhood Greenness to Heart Disease in 249 405 US Medicare Beneficiaries

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Nature exposures may be associated with reduced risk of heart disease. The present study examines the relationship between objective measures of neighborhood greenness (vegetative presence) and 4 heart disease diagnoses (acute myocardial ...
Kefeng Wang, Joanna Lombard, Tatjana Rundek, Chuanhui Dong, Carolina Marinovic Gutierrez, Margaret M. Byrne, Matthew Toro, Maria I. Nardi, Jack Kardys, Li Yi, José Szapocznik, Scott C. Brown   +11 more
doaj   +1 more source