Results 51 to 60 of about 59,843 (260)

Heart failure related to adult congenital heart disease: prevalence, outcome and risk factors

ESC Heart Failure, 2021
Aims Information on the prevalence, outcome and factors associated with heart failure in patients with adult congenital heart disease (CHD) (ACHD‐HF) is lacking.
Stijn Arnaert, Pieter De Meester, Els Troost, Walter Droogne, Lucas Van Aelst, Johan Van Cleemput, Gabor Voros, Marc Gewillig, Bjorn Cools, Philip Moons, Filip Rega, Bart Meyns, Zhenyu Zhang, Werner Budts, Alexander Van De Bruaene   +14 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

The prevalence of selected modifiable coronary heart disease risk factors in 12-year-old Greek boys and girls [PDF]

, 2007
The prevalence of 14 selected modifiable coronary heart disease (CHD) risk factors was determined in randomly selected adolescent boys (n = 117) and girls (n = 93) from provincial Greece.
Bouziotas, Constantin, Pananakakis, Yiannis, Koutedakis, Yiannis, Shiner, Ruth, Fotopoulou, Vasiliki   +4 more
core  

Evolution of cardiovascular risk factors and ischemic heart disease in an elderly urban Romanian population over the course of 1 year

Clinical Interventions in Aging, 2013
Dana Pop, Alexandra Dădârlat, Mihnea Zdrenghea, Dumitru Tudor Zdrenghea, Adela Viviana Sitar-Taăut Faculty of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania Background: Romania has some of the highest mortality
Pop D, Dǎdârlat A, Zdrenghea M, Zdrenghea DT, Sitar-Tǎut AV   +4 more
doaj  

Risk Factors in Heart Disease: Therapeutic Interventions [PDF]

Antioxidants & Redox Signaling, 2011
Many investigators continue to labor assiduously to elucidate the seemingly endless operant conditions resulting in cardiovascular disease. In aggregate, this work continues to categorize the complex sets of responses of the cardiomyocyte to noxious stimuli. This Forum aims to explore newer concepts and mechanisms contributing to heart tissue injury as
Nilanjana, Maulik, Juan A, Sanchez
openaire   +2 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Genetic variants of Y chromosome are associated with a protective lipid profile in black men [PDF]

, 2008
Objective— Gender and ethnicity modulate the phenotypic expression of cardiovascular risk factors. In particular, men are at higher risk of developing cardiovascular diseases compared to women, whereas black populations of African origin display reduced ...
Lauria, Fabio, Siani, Alfonso, Michelle A. Miller, Barba, Gianvincenzo, Fabio Lauria, Alfonso Siani, Karanam, Sharada, O Gianfrancesco, Gianfrancesco, Fernando, Paola Russo, Teresa Esposito, Esposito, Teresa, Strazzullo, Pasquale, Cappuccio, Francesco, Pasquale Strazzullo, Sharada Karanam, Gianvincenzo Barba, Miller, Michelle A., Russo, Paola   +18 more
core   +1 more source

Risk factors for asymptomatic echocardiographic abnormalities that predict symptomatic heart failure

ESC Heart Failure, 2022
Aims Risk factors for asymptomatic echocardiographic abnormalities that predict symptomatic heart failure (HF) may provide insight into early mechanisms of HF pathogenesis.
Jennifer M. Coller, Fei Fei Gong, Michele McGrady, Louise Shiel, Danny Liew, Simon Stewart, Alice J. Owen, Henry Krum, Christopher M. Reid, David L. Prior, Duncan J. Campbell   +10 more
doaj   +1 more source