Results 1 to 10 of about 2,716,079 (354)

A review of the molecular mechanisms underlying the development and progression of cardiac remodeling [PDF]

open access: yes, 2017
Pathological molecular mechanisms involved in myocardial remodeling contribute to alter the existing structure of the heart, leading to cardiac dysfunction.
Angelini, Francesco   +15 more
core   +3 more sources

Role of the Kidney in the Pathogenesis of Congestive Heart Failure [PDF]

open access: bronze, 1959
A. C. Barger   +2 more
openalex   +1 more source

Characterising an Alternative Murine Model of Diabetic Cardiomyopathy

open access: yesFrontiers in Physiology, 2019
The increasing burden of heart failure globally can be partly attributed to the increased prevalence of diabetes, and the subsequent development of a distinct form of heart failure known as diabetic cardiomyopathy.
Mitchel Tate   +21 more
doaj   +1 more source

Effects of Cardiac Structural Remodelling During Heart Failure on Cardiac Excitation – Insights from a Heterogeneous 3D Model of the Rabbit Atria [PDF]

open access: yes, 2015
Heart failure is a leading cause of morbidity and mortality in the western world. One of the effects of heart failure is the structural remodelling of cardiac tissue, including tissue dilation and development of fibrosis.
Boyett, Mark   +7 more
core   +2 more sources

Association between self-reported and objectively assessed physical functioning in the general population

open access: yesScientific Reports
Knowledge about a patient’s physical fitness can aid in medical decision-making, but objective assessment can be challenging and time-consuming. We aimed to investigate the concordance of self-reported health status and physical functioning with the 6 ...
Nicola Moser   +9 more
doaj   +1 more source

CXCR4 Antagonism Reduces Cardiac Fibrosis and Improves Cardiac Performance in Dilated Cardiomyopathy

open access: yesFrontiers in Pharmacology, 2019
Background: Myocardial fibrosis is a key pathologic finding in the failing heart and is implicated as a cause of increased ventricular stiffness and susceptibility to ventricular arrhythmia.
Po-Yin Chu   +5 more
doaj   +1 more source

Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure. [PDF]

open access: yes, 2019
The development of new treatments for heart failure lack animal models that encompass the increasingly heterogeneous disease profile of this patient population.
Alex, Linda   +22 more
core  

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