Risk factors for heart failure in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl [PDF]
Background: A phase 3 randomized clinical trial was designed to test whether bardoxolone methyl, a nuclear factor erythroid-2–related factor 2 (Nrf2) activator, slows progression to end-stage renal disease in patients with stage 4 chronic kidney disease
Bakris, George L.+10 more
core +8 more sources
Effects of Cardiac Structural Remodelling During Heart Failure on Cardiac Excitation – Insights from a Heterogeneous 3D Model of the Rabbit Atria [PDF]
Heart failure is a leading cause of morbidity and mortality in the western world. One of the effects of heart failure is the structural remodelling of cardiac tissue, including tissue dilation and development of fibrosis.
Boyett, Mark+7 more
core +2 more sources
‘Hearts and minds’: association, causation and implication of cognitive impairment in heart failure [PDF]
The clinical syndrome of heart failure is one of the leading causes of hospitalisation and mortality in older adults. An association between cognitive impairment and heart failure is well described but our understanding of the relationship between the ...
Cannon, Jane A.+2 more
core +4 more sources
Spatial variation of heart failure and air pollution in Warwickshire, UK : an investigation of small scale variation at the ward-level [PDF]
Objectives To map using geospatial modelling techniques the morbidity and mortality caused by heart failure within Warwickshire to characterise and quantify any influence of air pollution on these risks. Design Cross-sectional. Setting Warwickshire,
Bennett, Oscar+4 more
core +1 more source
Ensemble Framework for Cardiovascular Disease Prediction [PDF]
Heart disease is the major cause of non-communicable and silent death worldwide. Heart diseases or cardiovascular diseases are classified into four types: coronary heart disease, heart failure, congenital heart disease, and cardiomyopathy. It is vital to diagnose heart disease early and accurately in order to avoid further injury and save patients ...
arxiv +1 more source
Limited availability of cardiac rehabilitation for heart failure patients in the United Kingdom: findings from a national survey [PDF]
Background: Participation of patients with heart failure in cardiac rehabilitation in the UK is low. This study investigated the availability of cardiac rehabilitation services for patients with heart failure in the UK and the views of service ...
Buttery, Amanda K+4 more
core +1 more source
National survey of the prevalence, incidence, primary care burden, and treatment of heart failure in Scotland [PDF]
Objective: To examine the epidemiology, primary care burden, and treatment of heart failure in Scotland, UK. Design: Cross sectional data from primary care practices participating in the Scottish continuous morbidity recording scheme between 1 April ...
Capewell, S.+9 more
core +2 more sources
Mihai Gheorghiade, MD-Life and Concepts [PDF]
How do you capture an idea, shape it, and then bring it into the world? Of his many talents, this ability was a fundamental characteristic of Mihai Gheorghiade.
Butler, Javed+3 more
core +1 more source
Randomised controlled trial of specialist nurse intervention in heart failure [PDF]
<p>Objectives. To determine whether specialist nurse intervention improves outcome in patients with chronic heart failure.</p> <p>Design. Randomised controlled trial.</p> <p>Setting.
Blue, L.+11 more
core +2 more sources
Leveraging Natural Learning Processing to Uncover Themes in Clinical Notes of Patients Admitted for Heart Failure [PDF]
Heart failure occurs when the heart is not able to pump blood and oxygen to support other organs in the body as it should. Treatments include medications and sometimes hospitalization. Patients with heart failure can have both cardiovascular as well as non-cardiovascular comorbidities.
arxiv