Results 241 to 250 of about 1,181,499 (316)

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Do obesity and visceral adiposity promote heart failure with reduced ejection fraction? [PDF]

Eur Heart J
Packer M.
europepmc   +1 more source

Programmable Compliance in Small‐Diameter Vascular Grafts by Design of Melt‐Electrowritten Scaffold Architectures for In Situ Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Small‐diameter vascular grafts with compliance tunable by design are fabricated via melt electrowriting. By controlling the winding angle of intertwined helical fibers, grafts with compliances matching those of human vessels, from veins to arteries, are realized. This holds the potential of avoiding a compliance mismatch, which has been identified as a
Kilian Maria Arthur Mueller, Christina Ahrens, Linda Grefen, Salma Mansi, Dario Arcuti, Elena De‐Juan‐Pardo, Felix Kur, Christian Hagl, Petra Mela   +8 more
wiley   +1 more source

Controlling Intestinal Organoid Polarity using Synthetic Dynamic Hydrogels Decorated with Laminin‐Derived IKVAV Peptides

Advanced Healthcare Materials, EarlyView.
Design rules are presented to control intestinal organoid polarity in fully synthetic hydrogels. The laminin‐derived IKVAV sequence is crucial to obtain correct intestinal organoid polarity. Increasing hydrogel dynamics further supports the growth of correctly polarized intestinal organoids, while a bulk level of stiffness (G’ ≈ 0.7 kPa) is crucial to ...
Laura Rijns, Joost A. P. M. Wijnakker, Victor A. Veenbrink, Riccardo Bellan, Fenna W. B. Craenmehr, Simone I. S. Hendrikse, Johnick F. van Sprang, Wim de Lau, E. W. Meijer, Hans Clevers, Patricia Y. W. Dankers   +10 more
wiley   +1 more source

Integrated Care in Patients with Atrial Fibrillation and Optimal Medical Treatment for Heart Failure: Results from the Heart failuRe ObsErvational Study (HEROES). [PDF]

J Clin Med
Gorczyca-Głowacka I, Molenda K, Nadel M, Galas A, Tymińska A, Byczkowska K, Siniarski A, Furmanek W, Stefański A, Wożakowska-Kapłon B, Klimczak-Tomaniak D, Morawiec R.   +11 more
europepmc   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Linking Myocardium Hypercontractility to Microvasculature Dysfunction and Inflammation through NLRP3 Inflammasome Activation

Journal of Molecular and Cellular Cardiology Plus
Vasco Sequeira, Katharina Ermer, Jan M. Federspiel, Mark Waddingham, Jan Dudek, Hirotsugu Tsuchimochi, Christoph Maack, James Pearson   +7 more
doaj   +1 more source

Echocardiographic Alterations in Subjects with Sarcopenia and Right Heart Failure. [PDF]

Med Sci (Basel)
Orea-Tejeda A, Delgado-Pérez LA, Valderrábano-Salas B, González-Islas D, Montañez-Orozco Á, Ruan-Díaz JC, Hernández-Hernández MJ, Lozano-Hernández E, Chávez-Guzmán CP, García-Díaz K.   +9 more
europepmc   +1 more source

Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate

Advanced Healthcare Materials, EarlyView.
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang, Peiyuan Wang, Hildert Bronkhorst, Yurii Husiev, Ludovic Bretin, Maarten N. van Ginkel, Wen Sun, Sylvestre Bonnet   +7 more
wiley   +1 more source