Results 151 to 160 of about 65,782,767 (266)

UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz, Pimrapat Gebert, Jingwen Luo, Paraskevi Tassopoulou, Juliane Bolbrinker, Antonios Douros   +5 more
wiley   +1 more source

Hope for heart failure with preserved ejection fraction? [PDF]

Sci Adv
Blanton RM.
europepmc   +1 more source

Research Progress of Three‐Terminal Perovskite/Silicon Tandem Solar Cells Based on Back‐Contact Silicon

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Perovskite/silicon tandem solar cells offer efficiencies beyond 30%, yet conventional architectures face trade‐offs between optical performance and current matching. Three‐terminal tandems employing silicon back‐contact bottom cells eliminate the current‐matching constraint while minimizing optical losses, offering superior energy yield under real ...
Yunhao Fan, Sheng Ma, Huanpei Huang, Zhengping Li, Wenzhong Shen   +4 more
wiley   +1 more source

Usefulness of Strain Echocardiography in Heart Failure with Preserved Ejection Fraction. [PDF]

J Clin Med
Pastore MC, Carmona De Azevedo Bellagamba C, Stefanini A, Pinelli A, Mandoli GE, Cavigli L, D'Ascenzi F, Focardi M, Cameli M.   +8 more
europepmc   +1 more source

Advanced cardiac imaging and haemodynamic assessment following isometric exercise training in heart failure with preserved ejection fraction [PDF]

Hypertension is as a leading attributable risk factor for cardiovascular disease and premature mortality. Global initiatives towards the prevention and treatment of arterial hypertension are centred around non-pharmacological lifestyle modification ...
Edwards, J.
core  

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Belzutifan-Associated Reversible Heart Failure With Preserved Ejection Fraction in Metastatic Renal Cell Carcinoma. [PDF]

IJU Case Rep
Kimura H, Nakazawa S, Ishizuya Y, Yamamoto Y, Takezawa K, Kato T, Hatano K, Kakuta Y, Kawashima A, Nonomura N.   +9 more
europepmc   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu, Zhenbang Gu, Wengen Zhu, Shenghui Feng   +3 more
wiley   +1 more source

Immunometabolic regulation of cardiac macrophages in heart failure with preserved ejection fraction. [PDF]

Front Immunol
Liang J, Su M, Liu R, Li T, Qin Z, Wang Y.   +5 more
europepmc   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source