Results 141 to 150 of about 179,384 (308)

Improving Postdischarge Outcomes in Acute Heart Failure [PDF]

, 2018
The global burden that acute heart failure (AHF) carries has remained unchanged over the past several decades (1). European registries (2–5) showed that 1-year outcome rates remain unacceptably high (Table 1) and confirm that hospitalization for AHF ...
Ambrosy, Andrew P., Antohi, Elena-Laura, Butler, Javed, Chioncel, Ovidiu, Collins, Sean P., Iliescu, Vlad Anton, Maggioni, Aldo P., Mebazaa, Alexandre, Pang, Peter S.   +8 more
core   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Central and Obstructive Apneas in Heart Failure With Reduced, Mid-Range and Preserved Ejection Fraction

Frontiers in Cardiovascular Medicine, 2019
Background: Although central apneas (CA) and obstructive apneas (OA) are highly prevalent in heart failure (HF), a comparison of apnea prevalence, predictors and clinical correlates in the whole HF spectrum, including HF with reduced ejection fraction ...
Chiara Borrelli, Chiara Borrelli, Chiara Borrelli, Francesco Gentile, Paolo Sciarrone, Gianluca Mirizzi, Gianluca Mirizzi, Giuseppe Vergaro, Giuseppe Vergaro, Nicolò Ghionzoli, Francesca Bramanti, Giovanni Iudice, Claudio Passino, Claudio Passino, Michele Emdin, Michele Emdin, Alberto Giannoni, Alberto Giannoni   +17 more
doaj   +1 more source

Resetting the neurohormonal balance in heart failure (HF). the relevance of the natriuretic peptide (NP) system to the clinical management of patients with HF [PDF]

, 2017
The natriuretic peptide (NP) system, which includes atrial natriuretic peptide, B-type natriuretic peptide, and C-type natriuretic peptide, has an important role in cardiovascular homeostasis, promoting a number of physiological effects including ...
Rubattu, Speranza Donatella, Triposkiadis, Filippos   +1 more
core   +2 more sources

Fiber‐type soft bioelectronics for wearable and implantable sensing and therapy

BMEMat, EarlyView.
Fiber‐type soft bioelectronics are emerging as versatile platforms for wearable and implantable health monitoring and therapeutic applications. These bioelectronics use organic and inorganic matrices combined with advanced fillers, which feature high conductivity, electrochemical sensitivity, softness, and biocompatibility.
Haneul Kim, Hak Yong Kim, Ja Hoon Koo, Gi Doo Cha, Dae‐Hyeong Kim, Hye Jin Kim   +5 more
wiley   +1 more source

Heart failure with preserved left ventricular ejection fraction – clinical perspectives

Annales Academiae Medicae Silesiensis
Heart failure with preserved ejection fraction (HFpEF) is an increasingly recognized subtype of heart failure, particularly affecting older adults and women.
Małgorzata Niemiec, Bartosz Gruchlik, Nicola Dyrek, Jan Niemiec, Bartosz Basiaga, Krzysztof Bednarz, Dorota Piłat, Kinga Czepczor, Maciej Podolski, Katarzyna Mizia-Stec   +9 more
doaj   +1 more source

Progression of coronary microvascular dysfunction to heart failure with preserved ejection fraction: a case report

Journal of Medical Case Reports, 2019
Background In women with evidence of ischemia and no obstructive coronary artery disease the underlying mechanism is most often attributed to coronary microvascular dysfunction.
Sandy Joung, Janet Wei, Michael D. Nelson, Haider Aldiwani, Chrisandra Shufelt, Balaji Tamarappoo, Daniel Berman, Louise E. J. Thomson, C. Noel Bairey Merz   +8 more
doaj   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Clonal Hematopoiesis and Incident Heart Failure With Preserved Ejection Fraction

JAMA Network Open
Key Points Question Are clonal hematopoiesis of indeterminate potential (CHIP) or certain CHIP driver genes associated with a specific heart failure (HF) subtype?
A. Schuermans, M. Honigberg, L. Raffield, Bing Yu, Mary B Roberts, C. Kooperberg, Pinkal M. Desai, April P. Carson, Amil M. Shah, C. Ballantyne, A. Bick, Pradeep Natarajan, J. Manson, E. Whitsel, Charles B. Eaton, Alex P. Reiner   +15 more
semanticscholar   +1 more source

Intravascular Lithotripsy Is Associated With Superior Clinical Outcomes Compared to Atherectomy: A Large‐Scale, Propensity‐Matched Analysis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery disease (CAD) with severe calcification remains a growing challenge in percutaneous coronary intervention (PCI). Atherectomy (ATH) has long been used for plaque modification, whereas intravascular lithotripsy (IVL) has emerged as a promising alternative. Large‐scale comparative data on long‐term outcomes are limited.
Charles D. Miks, Grant K. Ozaki, Chirayu R. Shukla, Vikram Sharma   +3 more
wiley   +1 more source