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Heart Failure with Preserved Ejection Fraction
AJN, American Journal of NursingABSTRACT Heart failure with preserved ejection fraction (HFpEF) is a multifaceted cardiovascular syndrome of symptomatic heart failure in which the left ventricular EF is normal (> 50%). The prevalence of HFpEF is rising and now accounts for approximately half of all heart failure cases worldwide, affecting an estimated 32 million ...
Antonio, Cannata, Theresa A, McDonagh
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Heart Failure With Preserved Ejection Fraction
JAMA, 2023ImportanceHeart failure with preserved ejection fraction (HFpEF), defined as HF with an EF of 50% or higher at diagnosis, affects approximately 3 million people in the US and up to 32 million people worldwide. Patients with HFpEF are hospitalized approximately 1.4 times per year and have an annual mortality rate of approximately 15%.ObservationsRisk ...
Margaret M, Redfield, Barry A, Borlaug
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Dapagliflozin in Heart Failure with Preserved Ejection Fraction
New England Journal of Medicine, 2023To the Editor: Solomon et al. (Sept. 22 issue)(1) report on the Dapagliflozin Evaluation to Improve the Lives of Patients with Preserved Ejection Fraction Heart Failure (DELIVER) trial, which showed reduced risks of heart failure-related outcomes (hospitalization for heart failure or an urgent visit for heart failure) among patients with a mildly ...
Domenico Gabrielli +2 more
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Heart Failure with Preserved Ejection Fraction in Children
Pediatric Cardiology, 2022Diastolic dysfunction (DD) refers to abnormalities in the mechanical function of the left ventricle (LV) during diastole. Severe LVDD can cause symptoms and the signs of heart failure (HF) in the setting of normal or near normal LV systolic function and is referred to as diastolic HF or HF with preserved ejection fraction (HFpEF).
Bibhuti Das +5 more
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Aging and Heart Failure with Preserved Ejection Fraction
Comprehensive Physiology, 2022Abstract Heart failure is a clinical syndrome characterized by the inability of the cardiovascular system to provide adequate cardiac output at normal filling pressures. This results in a clinical syndrome characterized by dyspnea, edema, and decreased exertional tolerance.
Kathryn F, Larson +2 more
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Obesity and Heart Failure with Preserved Ejection Fraction
Heart Failure Clinics, 2021Obese heart failure with preserved ejection fraction (HFpEF) is a distinct HFpEF phenotype. Sodium retention, high circulating neurohormone levels, alterations in energy substrate metabolism, group 3 pulmonary hypertension, pericardial restraint, and systemic inflammation are central pathophysiologic mechanisms.
Efstratios, Koutroumpakis +3 more
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Imaging in Heart Failure with Preserved Ejection Fraction
Heart Failure Clinics, 2014Heart failure (HF) with preserved ejection fraction (HFpEF) is becoming the predominant form of HF. Understanding cardiac structure and function in this syndrome is highly relevant for diagnosis, prognosis, pathophysiology, and management. However, identifying cardiac dysfunction in HFpEF can be challenging and requires an integrated assessment of ...
Deepak K, Gupta, Scott D, Solomon
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Heart Failure with Preserved Ejection Fraction in Women
Heart Failure Clinics, 2019Heart failure with preserved ejection fraction (HFpEF) is an increasingly prevalent condition, particularly in women. Comorbidities, including older age, obesity, diabetes mellitus, hypertension, and hyperlipidemia, are risk factors and define phenotypic profiles of HFpEF in women.
Anjan, Tibrewala, Clyde W, Yancy
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Epidemiology of heart failure with preserved ejection fraction
Nature Reviews Cardiology, 2017Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical syndrome associated with poor quality of life, substantial health-care resource utilization, and premature mortality. We summarize the current knowledge regarding the epidemiology of HFpEF with a focus on community-based studies relevant to quantifying the population burden of ...
Shannon M, Dunlay +2 more
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Heart failure with a preserved ejection fraction
British Journal of Hospital Medicine, 2013D R, Warriner +3 more
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