Results 251 to 260 of about 179,384 (308)

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao, Jing Zhou, Jing Wang, Si‐Nan Zhao, Zhan‐Sheng Zhao, Qian Wang, Ya‐Nan Xie, Wei Jiao   +7 more
wiley   +1 more source

Left ventricular hypertrophy and myocardial fibrosis in heart failure with preserved ejection fraction: mechanisms and treatment. [PDF]

Eur Heart J
Peikert A, Fontana M, Solomon SD, Thum T.   +3 more
europepmc   +1 more source

Early Dapagliflozin and Melatonin Treatment Ameliorated LV Fibrosis via Suppressing TGF‐β1/Smads and Activating Nrf2‐ARE Signaling in MI Rodent

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study tested whether combined dapagliflozin (DAPA) and melatonin (Mel) therapy was superior to merely one for ameliorating the left ventricular (LV) fibrosis/remodeling and improving LV ejection fraction (LVEF) in rats after acute myocardial infarction (AMI). In vitro study demonstrated that DAPA treatment significantly suppressed the TGF‐
Jiunn‐Jye Sheu, Jui‐Ning Yeh, Han‐Tan Chai, John Y. Chiang, Chi‐Ruei Huang, Jun Guo, Hon‐Kan Yip   +6 more
wiley   +1 more source

The diagnostic value of left atrial stiffness for heart failure with preserved ejection fraction in patients with paroxysmal atrial fibrillation. [PDF]

Echo Res Pract
Lai J, Qin X, Zhang D, Wang J, Yu J, Sun K, Yang D, Fan J, Zhang L, Cheng Z, Cheng K, Gao P, Deng H, Fang L, Chen T, Fang Q, Liu Y.   +16 more
europepmc   +1 more source

Response to the Nephrological perspectives on the underutilization of SGLT2i in heart failure and chronic kidney disease

ESC Heart Failure, Volume 12, Issue 2, Page 1492-1493, April 2025.
Umut Kocabas
wiley   +1 more source

Advances in Position‐Momentum Entanglement: A Versatile Tool for Quantum Technologies

Laser &Photonics Reviews, EarlyView.
Position–momentum entanglement constitutes a high‐dimensional continuous‐variable resource in quantum optics. Recent advances in its generation, characterization, and control are reviewed, with emphasis on spontaneous parametric down‐conversion and modern measurement techniques.
Satyajeet Patil, Rajshree Swarnkar, Jonas L. Moos, Sebastian Töpfer, Sergio Tovar‐Pérez, Jorge Fuenzalida, Markus Gräfe   +6 more
wiley   +1 more source

Immuno-haemostatic dysregulation in heart failure with preserved ejection fraction. [PDF]

ESC Heart Fail
D'Italia G, Coenen DM, Lemmens TP, Brandts L, Wielders SJH, Nagy M, Mourmans SGJ, Achten A, Al-Abadi A, Weerts J, Aizpurua AB, van Empel V, Schroen B, Cosemans JMEM.   +13 more
europepmc   +1 more source

Nephrological perspectives on the underutilization of SGLT2is in heart failure and chronic kidney disease

ESC Heart Failure, Volume 12, Issue 2, Page 1490-1491, April 2025.
Özant Helvacı, Ömer Faruk Akçay, Emre Yaşar, Ülver Derici, Galip Güz   +4 more
wiley   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Unravelling the Pathogenesis of Heart Failure with Preserved Ejection Fraction: The Pivotal Role of Autophagy and Endoplasmic Reticulum Stress. [PDF]

Eur Cardiol
Kencono Wungu CD, Susilo H, Susanto CR, Wijaya J, Kevin K, Wardhana DM, Nugraha D, Christodoulou R, Solomou E, Papageorgiou P.   +9 more
europepmc   +1 more source