Results 261 to 270 of about 179,384 (308)

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Effect of GLP-1 Receptor Agonists in Heart Failure with Preserved Ejection Fraction: A Systematic Review and Meta-Analysis. [PDF]

J Cardiovasc Dev Dis
Behers BJ, Sanchez C, Hozayen O, Hozayen Y, Kammer R, Corrigan WT, Stephenson-Moe CA, Miller MW, Idriss M, Cekan LE, King AD, Brown GH, Hamad KM.   +12 more
europepmc   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Right ventricular stiffness as a key feature in the ZSF1 model of heart failure with preserved ejection fraction. [PDF]

Eur Heart J Imaging Methods Pract
Schlotter F, Kresoja KP, Rommel KP, Rosenbusch L, Werner S, Sharma U, Thiele H, Besler C, Lurz P, Büttner P.   +9 more
europepmc   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Current Treatment of Heart Failure with Preserved Ejection Fraction. [PDF]

J Clin Med
Riccardi M, D'Elia E, Lombardi CM, Savarese G, Gori M, Oliva F, Volterrani M, Senni M, Metra M, Inciardi RM.   +9 more
europepmc   +1 more source

Beyond GLP‐1: The Cardiometabolic Potential of Dual GLP‐1/GIP Receptor Agonists

iNew Medicine, EarlyView.
Chao Xue
wiley   +1 more source

Inflammation, Immunity, and Cardiovascular Diseases

Med Research, EarlyView.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo, Yan Liao, Rui Zhao, Zhaoyu Li, Kaikai Wang, Haoling Zhang, Pingxin Sun, Yadong Guo, Wangzheqi Zhang   +8 more
wiley   +1 more source

Modifying the structural substrate and progression of heart failure with preserved ejection fraction using a regular exercise regimen in pigs. [PDF]

Am J Physiol Heart Circ Physiol
Samani SL, Barlow SC, Freeburg LA, Catherwood GM, Churillo AM, Jones TL, Al-Soudi J, Ruiz R, Yigamawano FK, Shazly T, Zile MR, Spinale FG.   +11 more
europepmc   +1 more source

Saplings of significance: Nurturing cultural value of new tree plantings through participatory opportunities

People and Nature, EarlyView.
Abstract Tree‐planting initiatives are a crucial part of international sustainability and climate action efforts. Yet, many of these initiatives fail to achieve their long‐term sustainability and climate goals. The role of community value is an often‐overlooked factor in promoting the success of new tree plantings.
Claire L. Narraway, Eline van Remortel, Sophie B. Cowling, Divya Kumar, Hanna Mroczka, Emilija Rudzinskaite, Georgina Sturgeon, Sasha Woods, Daniel B. Hayhow   +8 more
wiley   +1 more source