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Heart Failure With Preserved Ejection Fraction
Abstract Heart failure with preserved ejection fraction (HFpEF) is a complex clinical condition. Initially called diastolic heart failure, it soon became clear that this condition is more than the opposite side of systolic heart failure. It is increasingly prevalent and lethal.
F. Rogers+3 more
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Heart failure with preserved ejection fraction. [PDF]
It is now well established that among patients with the clinical syndrome of heart failure (HF), approximately half have preserved systolic function, known most commonly as heart failure with preserved ejection fraction (HFpEF). Although originally considered to be predominantly a syndrome that pathophysiologically involves abnormalities in diastolic ...
J. Udelson
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Heart failure with preserved ejection fraction.
New England Journal of Medicine, 2006A. Ahmed, J. Fleg, M. Gheorghiade
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Heart Failure With Preserved Ejection Fraction
Heart Failure Clinics, 2021Umair Khalid, A. Deswal
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Heart Failure With Preserved Ejection Fraction: A Review.
Journal of the American Medical Association (JAMA), 2023Importance Heart failure with preserved ejection fraction (HFpEF), defined as HF with an EF of 50% or higher at diagnosis, affects approximately 3 million people in the US and up to 32 million people worldwide.
M. Redfield, B. Borlaug
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Epidemiology of heart failure with preserved ejection fraction
Nature Reviews Cardiology, 2017Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical syndrome associated with poor quality of life, substantial health-care resource utilization, and premature mortality. We summarize the current knowledge regarding the epidemiology of HFpEF with a focus on community-based studies relevant to quantifying the population burden of ...
S. Dunlay, V. Roger, M. Redfield
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Cardiovascular Research, 2022
Obesity and heart failure (HF) with preserved ejection fraction (HFpEF) represent two intermingling epidemics driving perhaps the greatest unmet health problem in cardiovascular medicine in the 21st century. Many patients with HFpEF are either overweight
B. Borlaug+5 more
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Obesity and heart failure (HF) with preserved ejection fraction (HFpEF) represent two intermingling epidemics driving perhaps the greatest unmet health problem in cardiovascular medicine in the 21st century. Many patients with HFpEF are either overweight
B. Borlaug+5 more
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Obesity and Heart Failure with Preserved Ejection Fraction
Heart Failure Clinics, 2021Obese heart failure with preserved ejection fraction (HFpEF) is a distinct HFpEF phenotype. Sodium retention, high circulating neurohormone levels, alterations in energy substrate metabolism, group 3 pulmonary hypertension, pericardial restraint, and systemic inflammation are central pathophysiologic mechanisms.
Efstratios Koutroumpakis+3 more
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Heart failure with preserved ejection fraction
Nature Reviews Disease PrimersHeart failure with preserved ejection fraction (HFpEF) accounts for nearly half of all heart failure cases and has a prevalence that is expected to rise with the growing ageing population. HFpEF is associated with significant morbidity and mortality.
Carine E. Hamo+6 more
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