Results 121 to 130 of about 6,649,603 (308)

A model of heart rate kinetics in response to exercise [PDF]

open access: yes, 2008
We present a mathematical model, in the form of two coupled ordinary differential equations, for the heart rate kinetics in response to exercise. Our heart rate model is an adaptation of the model of oxygen uptake kinetics of Stirling: a physiological ...
Stirling, James   +3 more
core  

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

open access: yesAdvanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen   +17 more
wiley   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

open access: yesAdvanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee   +6 more
wiley   +1 more source

MS

open access: yes, 2008
thesisThe purpose of this descriptive study was to determine the relationship between the fetal heart rate during the last trimester of pregnancy and the sex of the baby.
Nash, Teresa Burt
core  

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

open access: yesAdvanced Science, EarlyView.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor   +11 more
wiley   +1 more source

Fetal Heart Rate Monitoring [PDF]

open access: yesJournal of Health & Medical Informatics, 2014
openaire   +2 more sources

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

open access: yesAdvanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao   +7 more
wiley   +1 more source

The effects of an ultra-endurance event on heart rate variability and cognitive performance during induced stress in Ironman triathletes [PDF]

open access: yes, 2009
Includes abstract.Includes bibliographical references (leaves 55-79).The effects of long-term participation in ultra-endurance exercise on the cardiovascular system have recently been the subject of much interest.
Joubert, Ilse
core   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

Intrapartum fetal heart rate monitoring using a handheld Doppler versus Pinard stethoscope: a randomized controlled study in Dar es Salaam

open access: yes, 2018
Benjamin A Kamala,1,2 Hussen L Kidanto,3,4 Peter J Wangwe,2,5 Ingvild Dalen,3 Estomih R Mduma,3,6 Jeffrey M Perlman,7 Hege L Ersdal1,8 1Faculty of Health Sciences, University of Stavanger, Stavanger, Norway; 2Department of Obstetrics and Gynecology ...
Kidanto HL   +6 more
core  

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