A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle
This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin +9 more
wiley +1 more source
Heart regeneration from the whole-organism perspective to single-cell resolution. [PDF]
Chen X, Zhong X, Huang GN.
europepmc +1 more source
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang +8 more
wiley +1 more source
Diverging Liquid–Liquid Phase Separation Behavior of Different Recombinant Major Ampullate Spidroins
Fibers spun from the MaSp1‐derivative as well as MaSp1‐MaSp2‐mixtures provide a deeper insight into the assembly process of the spidroins and how hierarchical architectures of spider silk fibers could be achieved. ABSTRACT Spider silk fibers show exceptional mechanical properties, based on their underlying spider silk proteins (spidroins) as well as a ...
Tim Schiller +2 more
wiley +1 more source
Retraction Note: Kynurenine promotes neonatal heart regeneration by stimulating cardiomyocyte proliferation and cardiac angiogenesis. [PDF]
Zhang D +7 more
europepmc +1 more source
Controlled Pt–Pt fine structure in square‐planar Pt(II) complexes governs metal–metal‐to‐ligand charge‐transfer (MMLCT) state formation, exciton dynamics, and organic light‐emitting diode performance. Short Pt–Pt contacts in Pt(fppz)2 enable coherent metal–metal coupling, sub‐microsecond emission and an external quantum efficiency of 29%, whereas ...
Atul Shukla +15 more
wiley +1 more source
Microtubules Sequester Acetylated YAP in the Cytoplasm and Inhibit Heart Regeneration. [PDF]
Liu S +8 more
europepmc +1 more source
Cardiomyocyte proliferation and heart regeneration in adult Xenopus tropicalis evidenced by a transgenic reporter line. [PDF]
Lin XL +8 more
europepmc +1 more source
Bridging the Gap: Advances and Challenges in Heart Regeneration from In Vitro to In Vivo Applications. [PDF]
Watanabe T +4 more
europepmc +1 more source
PARP1 Promotes Heart Regeneration and Cardiomyocyte Proliferation. [PDF]
Shu J +6 more
europepmc +1 more source

