Results 61 to 70 of about 42,317 (250)

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

Journal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes, Claudia Camaioni, João B. Augusto, Kristopher Knott, Ellie Quinn, Gabriella Captur, Andreas Seraphim, George Joy, Petros Syrris, Perry M. Elliott, Saidi Mohiddin, Peter Kellman, Hui Xue, Luis R. Lopes, James C. Moon   +14 more
wiley   +1 more source

Association Between Maternal Folic Acid Supplementation and Congenital Heart Defects in Offspring in Birth Cohorts From Denmark and Norway

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Evidence linking individual‐level maternal folic acid supplementation to offspring risk of congenital heart defects is lacking. We investigated whether folic acid supplementation in early pregnancy reduces offspring risk of heart defects in 2 ...
Nina Øyen, Sjurdur F. Olsen, Saima Basit, Elisabeth Leirgul, Marin Strøm, Lisbeth Carstensen, Charlotta Granström, Grethe S. Tell, Per Magnus, Stein E. Vollset, Jan Wohlfahrt, Mads Melbye   +11 more
doaj   +1 more source

Case‐malformed signal detection and prioritisation using EUROmediCAT data for pharmacovigilance in pregnancy

British Journal of Clinical Pharmacology, EarlyView.
Aim Many women take medications during pregnancy. However, the risk to the fetus from most medications is uncertain. Congenital anomalies are one of the leading causes of infant death and contribute to long‐term disability. Signal detection methods can be used to systematically identify possible medication–anomaly associations that require further ...
Hannah Johnson, Helen Dolk, Maria Loane, Christine Damase‐Michel, Joanne Given, Hedvig Nordeng, Jorieke E. H. Bergman, Iain Carey, Elly Den Hond, Ester Garne, Florence Rouget, Lea Bruneau, Isabelle Monier, Anke Rissmann, Mary O'Mahony, Miriam Gatt, Renée Lutke, Joanna Sichitiu, Elisa Ballardini, Alessio Coi, Clara Cavero Carbonell, David Tucker, Joan Morris   +22 more
wiley   +1 more source

Changes in Serum Natriuretic Peptide Levels after Percutaneous Closure of Small to Moderate Ventricular Septal Defects

The Scientific World Journal, 2012
Background. B-type natriuretic peptide has been shown to be a very sensitive and specific marker of heart failure. In this study, we aimed to investigate the effect of percutaneous closure of ventricular septal defects with Amplatzer septal occluders on ...
Yuksel Kaya, Ramazan Akdemir, Huseyin Gunduz, Sani Murat, Orhan Bulut, İbrahim Kocayigit, M. Bulent Vatan, M. Akif Cakar, Ekrem Yeter, Harun Kilic, Mustafa Tarik Agac, Zeydin Acar   +11 more
doaj   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source

Long‐Term Trends in Cardiac Erosion After Transcatheter Closure of Atrial Septal Defects With the Amplatzer Septal Occluder

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Trends in cardiac erosion after closure of secundum atrial septal defects (ASD) with the Amplatzer Septal Occluder (ASO) have not been assessed since updates were made to the Instructions for Use in 2012 and 2018. This study evaluates the incidence and demographics of ASO erosion over time since its introduction in 1996.
Daniel S. Levi, Doff B. McElhinney
wiley   +1 more source

PROBLEMS OF SELECTING THERAPY FOR HEART FAILURE IN A NEWBORN

Мать и дитя в Кузбассе
Congenital heart defects are still a serious medical and social problem. The incidence of congenital heart defects varies widely and ranges from 2.4% to 14.15%.
Наталья Николаевна Лылова, Наталья Владимировна Коробкова, Григорий Валерьевич Вавин, Светлана Ивановна Елгина, Елена Владимировна Рудаева, Наталья Степановна Черных, Кира Борисовна Мозес, Арина Андреевна Сизинцева   +7 more
doaj  

Congenital heart defects in Williams syndrome

The Turkish Journal of Pediatrics, 2017
Williams syndrome (WS), also known as Williams-Beuren syndrome, is a rare genetic disorder involving multiple systems including the circulatory system.
Shi-Min Yuan
doaj   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

On the involvement of the second heart field in congenital heart defects

Comptes Rendus Biologies
Congenital heart defects (CHD) affect 1 in 100 live births and result from defects in cardiac development. Growth of the early heart tube occurs by the progressive addition of second heart field (SHF) progenitor cells to the cardiac poles.
Guijarro, Clara, Kelly, Robert G.
doaj   +1 more source