Results 51 to 60 of about 64,543 (306)

Balloon assisted technique for closure of large atrial septal defects [PDF]

, 2008
Amplatzer device closure of large atrial septal defects is challenging. A large device tends to malalign with the plane of the interatrial septum or prolapses through the defect.
Dalvi, Bharat V.
core  

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Patient with Ebstein anomaly and Down syndrome. Strange combination

Acta Pediátrica de México, 2014
The most common congenital heart diseases in children with Down syndrome are atrial or ventricular septal defects, patent ductus arteriosus or endocardial cushion defects.
Jesús de Rubens-Figueroa, Bruno Marino   +1 more
doaj   +1 more source

Accurate Detection of Septal Defects With Fetal Ultrasonography Images Using Deep Learning-Based Multiclass Instance Segmentation

IEEE Access, 2020
Accurate screening for septal defects is important for supporting radiologists' interpretative work. Some previous studies have proposed semantic segmentation and object detection approaches to carry out fetal heart detection; unfortunately, the models ...
Siti Nurmaini, Muhammad Naufal Rachmatullah, Ade Iriani Sapitri, Annisa Darmawahyuni, Adithia Jovandy, Firdaus Firdaus, Bambang Tutuko, Rossi Passarella   +7 more
doaj   +1 more source

Role of intergenic interactions between cytokine and Toll-like receptor genes in the etiology of congenital heart defects

Кардиоваскулярная терапия и профилактика, 2023
The incidence of congenital heart defects (CHDs) reaches 1% of all newborns. Of particular importance is the group of heart defects without a family history and chromosomal disorders, which makes up>80% of all CHDs.
A. V. Shabaldin, S. A. Shmulevich, A. V. Sinitskaya, R. Yu. Zamaraev   +3 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Centered Partition Process: Informative Priors for Clustering

, 2019
There is a very rich literature proposing Bayesian approaches for clustering starting with a prior probability distribution on partitions. Most approaches assume exchangeability, leading to simple representations in terms of Exchangeable Partition ...
Dunson, David B., Herring, Amy H., Olshan, Andrew F., Paganin, Sally   +3 more
core   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

From Multiple Congenital Anomalies to Pituitary Gland Malformation: Wide Spectrum of Clinical Features in a Family With FOXA2 Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT FOXA2 (hepatocyte nuclear factor‐3β, HNF‐3β) encodes a transcriptional activator involved in early embryogenesis, particularly in the patterning and differentiation of midline structures such as the neural tube, foregut, and pituitary gland. Its role in human pathogenesis was first suspected when patients with deletion of chromosome 20p11.2 ...
Christopher Connolly, Hemant A. Parmar, Lauren Hipp, Tomoyasu Higashimoto   +3 more
wiley   +1 more source

The Fate of the Outflow Tract Septal Complex in Relation to the Classification of Ventricular Septal Defects

Journal of Cardiovascular Development and Disease, 2019
It is now established that the entity often described as an “aortopulmonary septal complex„ is better considered as an “outflow tract septal complex„.
Robert H. Anderson, Justin T. Tretter, Diane E. Spicer, Shumpei Mori   +3 more
doaj   +1 more source