Results 151 to 160 of about 907,320 (349)

Lab‐Scale Continuous Biomanufacturing: A Tool for Process Development With Adaptive Strategies for Capture and Virus Inactivation

open access: yesBiotechnology and Bioengineering, EarlyView.
Schematic representation of the continuous lab‐scale process. ABSTRACT Monoclonal antibodies (mAbs) are nowadays fundamental in treating a wide range of severe diseases, including cancer, infections, or autoimmune disorders. Due to their high specificity, potent activity, and fewer side effects compared to small molecular drugs, the market for mAbs is ...
Thomas Kruse   +5 more
wiley   +1 more source

An intelligent Medical Cyber–Physical System to support heart valve disease screening and diagnosis

open access: hybrid, 2023
Gennaro Tartarisco   +10 more
openalex   +1 more source

Predictors of Maternal and Neonatal Complications in Patients With Severe Valve Heart Disease During Pregnancy [PDF]

open access: gold, 2020
Rania Hammami   +8 more
openalex   +1 more source

Macrophage‐targeted cerium‐tannic acid metal‐polyphenol framework nanoenzyme promotes in situ heart valves regeneration through adaptive immunomodulation

open access: yesBMEMat, EarlyView.
A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song   +9 more
wiley   +1 more source

A Meta‐Analysis and Simplified Nomenclature for Diagonal Coronary Artery and Ramus Intermedius Across Adult and Pediatric Hearts

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Anatomical descriptions of left‐sided oblique coronary branches remain inconsistent, hindering imaging interpretation and surgical planning. To quantify the prevalence, branching patterns and morphometry of the ramus intermedius (RI) and diagonal branches, and propose a unified nomenclature.
Yuqian Dai   +3 more
wiley   +1 more source

Adipocytes in Aortic Stenosis: Association With Clinical and Morphological Indices

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Recently, great attention has been given to understanding the new pathogenetic mechanisms underlying aortic stenosis (AS). The study aims to understand the role of mature adipocytes in AS and their association with histologic, clinical, and echocardiographic data, an area previously overlooked in AS research.
Elena Zoico   +9 more
wiley   +1 more source

Superiority of the Rockwood Clinical Frailty Scale for Assessing Long‐Term Outcome in Patients Undergoing Transcatheter Aortic Valve Implantation

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Frailty is associated with poorer short‐term outcomes after transcatheter aortic valve implantation (TAVI), and national guidelines recommend an assessment of frailty as part of the decision‐making process. However, multiple frailty indices are currently used in clinical practice, and it is unclear which has the best discrimination ...
Timothy J. Bagnall   +11 more
wiley   +1 more source

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