Results 41 to 50 of about 184,801 (293)

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

open access: yesAdvanced Science, EarlyView.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin   +15 more
wiley   +1 more source

Combined mitral valve repair and heart transplantation [PDF]

open access: yesClinical Case Reports, 2018
Key Clinical MessageIn times of donor organ shortage, organs with extended allocation criteria, for example, valve pathologies, have to be taken into consideration for transplantation. The donor pool can be extended to hearts with mitral valve insufficiency.
Anke Sprengel   +5 more
openaire   +1 more source

A Dual‐Modal Wearable Pulse Detection System Integrated with Deep Learning for High‐Accuracy and Low‐Power Sleep Apnea Monitoring

open access: yesAdvanced Science, EarlyView.
A dual‐modal wearable pulse detection system is developed for sleep apnea monitoring by integrating a self‐powered PENG and PPG sensor with a biomimetic fingertip structure. Through a two‐stage detection strategy, continuous PPW monitoring and on‐demand PPG detection achieve high‐accuracy sleep apnea recognition while maintaining low power consumption.
Jia Wang   +10 more
wiley   +1 more source

Nitric oxide synthase-3 promotes embryonic development of atrioventricular valves. [PDF]

open access: yesPLoS ONE, 2013
Nitric oxide synthase-3 (NOS3) has recently been shown to promote endothelial-to-mesenchymal transition (EndMT) in the developing atrioventricular (AV) canal.
Yin Liu   +4 more
doaj   +1 more source

Improvement of Rheumatic Valvular Heart Disease in Patients Undergoing Prolonged Antibiotic Prophylaxis

open access: yesFrontiers in Cardiovascular Medicine, 2021
Secondary prophylaxis of rheumatic heart diseases is efficient in reducing disease recurrence, heart damage, and cardiac impairment. We aimed to monitor the clinical evolution of a large Brazilian cohort of rheumatic patients under prolonged secondary ...
Renato Pedro de Almeida Torres   +11 more
doaj   +1 more source

'Edge-to-edge' mitral valve repair: the ace of hearts [PDF]

open access: yesEuropean Heart Journal, 2006
A 32-year-old man underwent a successful surgical correction of a severe mitral regurgitation. The surgical procedure consisted of an ‘edge-to-edge’ repair of the valve, connecting the mid-portion of the anterior and posterior leaflets, associated with implantation of a mitral annuloplasty ring (Sovering O 38 mm; …
ZACÀ V.   +3 more
openaire   +5 more sources

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

open access: yesAdvanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai   +9 more
wiley   +1 more source

On-pump fibrillating heart mitral valve replacement with the SAPIEN  XT transcatheter heart valve [PDF]

open access: yesEuropean Journal of Cardio-Thoracic Surgery, 2013
In some high-risk patients, standard mitral valve replacement can represent a challenging procedure, requiring a risky extensive decalcification of the annulus. In particular, high-risk redo patients and patients with a previously implanted transcatheter aortic valve, who develop calcific mitral disease, would benefit from the development of new ...
Ferrari, Enrico   +3 more
openaire   +4 more sources

Two‐Stage Treatment for Adult Large Patent Ductus Venosus

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This is the first report of a two‐stage treatment for an adult large PDV involving the first stage surgical angioplasty of the large Arantius' duct and second stage embolization of the formed small Arantius' duct. The two‐stage approach could avoid embolic material migration into the systemic circulation or acute portal hypertension associated with the
Shohei Kudo   +4 more
wiley   +1 more source

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