Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang +9 more
wiley +1 more source
A Geometric Feature Tracking Approach for Noninvasive Patient-Specific Estimation of Leaflet Strain from 3D Images of Heart Valves. [PDF]
Wu W +4 more
europepmc +1 more source
Drift Reduction in 2D PtSe2 Piezoresistive Pressure Sensors Through an On‐Chip Wheatstone Bridge
Drift is a major source of error affecting the accuracy and repeatability of sensors. A Wheatstone bridge (WSB) enables high sensitivity, accuracy, and the elimination of common‐mode drift. We apply the WSB concept to highly sensitive piezoresistive pressure sensors made with two‐dimensional layered platinum diselenide transducers.
Ragini Gupta +6 more
wiley +1 more source
Effective Recellularization Using Mesenchymal Stem Cell Monoculture for Next-Generation Heart Valves. [PDF]
Kim SY +7 more
europepmc +1 more source
Developing slurries for carbon capture: From synthetic gas mixtures to flue gas
Abstract Deep eutectic solvent (DES)‐based systems have recently emerged as promising alternatives to conventional liquid sorbents for CO2 capture due to their tunable properties and potential for enhanced mass transfer. In this work, two DES‐based slurry systems previously developed for CO2 capture, one aqueous and one non‐aqueous, were further ...
Sahar Foorginezhad +3 more
wiley +1 more source
Bioengineered heart valves for personalized therapy: advances in manufacturing and clinical challenges. [PDF]
Saeed M, Khan KA.
europepmc +1 more source
A machine learning‐guided self‐driving laboratory screened over 500 nickel‐based layered double‐hydroxide catalysts for alkaline oxygen evolution. Out of the eight metals, the robot uncovered a quaternary Ni–Fe–Cr–Co catalysts requiring only 231 mV overpotential to reach 20 mA cm−2.
Nis Fisker‐Bødker +3 more
wiley +1 more source
Resumption of Warfarin After Intracranial Hemorrhage in Patients With Mechanical Heart Valves: A Systematic Review and Meta-Analysis. [PDF]
Sakusic A +8 more
europepmc +1 more source
A low‐cost, self‐driving laboratory is developed to democratize autonomous materials discovery. Using this "frugal twin" hardware architecture with Bayesian optimization, the platform rapidly converges to target lower critical solution temperature (LCST) values while self‐correcting from off‐target experiments, demonstrating an accessible route to data‐
Guoyue Xu, Renzheng Zhang, Tengfei Luo
wiley +1 more source
Enzyme-responsive hydrogel coating for <i>in situ</i> re-endothelialization of bioprosthetic heart valves. [PDF]
Liang X +9 more
europepmc +1 more source

