Results 1 to 10 of about 117,950 (235)
Evaluation of pliable bioresorbable, elastomeric aortic valve prostheses in sheep during 12 months post implantation [PDF]
Communications Biology, 2023 Pliable microfibrous, bioresorbable elastomeric heart valve prostheses are investigated in search of sustainable heart valve replacement. These cell-free implants recruit cells and trigger tissue formation on the valves in situ. Our aim is to investigate
Annemijn Vis +14 more
doaj +5 more sources
Models of immunogenicity in preclinical assessment of tissue engineered heart valves
Acta Biomaterialia, 2021 Tissue engineered heart valves may one day offer an exciting alternative to traditional valve prostheses. Methods of construction vary, from decellularised animal tissue to synthetic hydrogels, but the goal is the same: the creation of a 'living valve ...
Marcus Ground +2 more
exaly +3 more sources
Journal of Cardiothoracic Surgery, 2020 Background Valve replacement surgery is the definitive management strategy for patients with severe valvular disease. However, valvular conduits currently in clinical use are associated with significant limitations.
Steve W. F. R. Waqanivavalagi +4 more
doaj +3 more sources
Mechanotransduction of autotransplants: remodeling potential of heart valves from autologous pericardial tissue [PDF]
Frontiers in Bioengineering and BiotechnologyCurrent commercial heart valve prostheses are non-living structures, either derived from artificial materials (mechanical valves) or foreign biological materials (xeno- or homo-graft).
Marvin Steitz +15 more
doaj +2 more sources
Arquivos Brasileiros de Cardiologia, 2002 OBJECTIVE: To investigate whether patients with heart valve prostheses and similar International Normalized Ratios (INR) have the same level of protection against thromboembolic events, that is, whether the anticoagulation intensity is related to the ...
Claudia Natália Ferreira +6 more
doaj +2 more sources
Antithrombotic Therapy in Patients with Prosthetic Heart Valves [PDF]
Libyan Journal of Medicine, 2009 Patients with mechanical valve prostheses require a lifelong anticoagulant treatment. The combined use of Warfarin and low-dose aspirin appears to reduce the risk of valve thrombosis and systemic embolism at a low risk of bleeding.
Mohamed HA
doaj +1 more source
A chronological history of heart valve prostheses to offer perspectives of their limitations
Frontiers in Bioengineering and BiotechnologyProsthetic heart valves (PHV) have been studied for around 70 years. They are the best alternative to save the life of patients with cardiac valve diseases. However, current PHVs may still cause significant disadvantages to patients.
Raquel Ahnert Aguiar Evangelista +3 more
doaj +3 more sources
Biocompatibility Issue Of Tissue Engineered Heart Valves
Archives of Metallurgy and Materials, 2015 Tissue engineering is a new field of knowledge which creates the possibilities for producing bioactive cardiac prostheses that will characterize by biomechanical and morphological properties similar to native tissue.
Wilczek P.
doaj +2 more sources
Structural evolution of mechanical heart valves (review)
Вестник трансплантологии и искусственных органовProsthetic heart valves are widely used biomedical devices. The need for these prostheses is increasing due to the increasing life expectancy of the general population and the consequent incidence of age-related degenerative valvular defects.
M. A. Lepilin +9 more
doaj +2 more sources
Tissue Engineering Heart Valves – a Review of More than Two Decades into Preclinical and Clinical Testing for Obtaining the Next Generation of Heart Valve Substitutes [PDF]
Romanian Journal of Cardiology, 2021 Well documented shortcomings of current heart valve substitutes – biological and mechanical prostheses make them imperfect choices for patients diagnosed with heart valve disease, in need for a cardiac valve replacement.
Dan SIMIONESCU +4 more
doaj +1 more source