Mechanotransduction of autotransplants: remodeling potential of heart valves from autologous pericardial tissue [PDF]
Current commercial heart valve prostheses are non-living structures, either derived from artificial materials (mechanical valves) or foreign biological materials (xeno- or homo-graft).
Marvin Steitz +15 more
doaj +2 more sources
Tissue Engineering Heart Valves – a Review of More than Two Decades into Preclinical and Clinical Testing for Obtaining the Next Generation of Heart Valve Substitutes [PDF]
Well documented shortcomings of current heart valve substitutes – biological and mechanical prostheses make them imperfect choices for patients diagnosed with heart valve disease, in need for a cardiac valve replacement.
Dan SIMIONESCU +4 more
doaj +1 more source
Pliable microfibrous, bioresorbable elastomeric heart valve prostheses are investigated in search of sustainable heart valve replacement. These cell-free implants recruit cells and trigger tissue formation on the valves in situ. Our aim is to investigate
Annemijn Vis +14 more
doaj +1 more source
Heart diseases caused by structure and function degradation is troubling millions of people all over the world. With the extension of human lifespan, the demand for heart valve replacement is rapidly increasing.
Ziyu Shao +10 more
doaj +1 more source
Fluid dynamic characterization of a polymeric heart valve prototype (Poli-Valve) tested under continuous and pulsatile flow conditions. [PDF]
PURPOSE: Only mechanical and biological heart valve prostheses are currently commercially available. The former show longer durability but require anticoagulant therapy; the latter display better fluid dynamic behavior but do not have adequate durability.
Bagnoli, Paola +6 more
core +8 more sources
Developing the Tissue Engineered Heart Valve – a Descriptive Hemodynamic and Ultrasound in Vitro Characterization Study of Heart Valves in a Bioreactor [PDF]
The inherent limitations of current heart valve substitutes create the premise for the Tissue Engineered Heart Valve (TEHV), considered the perfect substitute. We aimed to compare in vitro hemodynamic performances of our TEHV, the conventional prosthetic
Ionela MOVILEANU +13 more
doaj +1 more source
Remote Ischemic Preconditioning Neither Improves Survival nor Reduces Myocardial or Kidney Injury in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) [PDF]
BACKGROUND: Peri-interventional myocardial injury occurs frequently during transcatheter aortic valve implantation (TAVI). We assessed the effect of remote ischemic preconditioning (RIPC) on myocardial injury, acute kidney injury (AKIN) and 6-month ...
Flechsig, Mandy +14 more
core +1 more source
Comparative study of wall shear stress at the ascending aorta for different mechanical heart valve prostheses [PDF]
An experimental study is reported which investigates the wall shear stress (WSS) distribution in a transparent model of the human aorta comparing a bileaflet mechanical heart valve (BMHV) with a trileaflet mechanical heart valve (TMHV) in physiological ...
Bruecker, C., Li, Q.
core +1 more source
Bridging aortic valve surgery to 21st century. what can a surgeon do [PDF]
Aortic valve stenosis is the most clinically relevant valvular heart disease in the elderlies. Surgical aortic valve replacement (SAVR) represented, for decades, the standard of care for the treatment of severe aortic stenosis.
Barretta, Antonio +13 more
core +1 more source
Guided Tissue Regeneration in Heart Valve Replacement: From Preclinical Research to First-in-Human Trials [PDF]
Heart valve tissue-guided regeneration aims to offer a functional and viable alternative to current prosthetic replacements. Not requiring previous cell seeding and conditioning in bioreactors, such exceptional tissue engineering approach is a very ...
Gerosa, Gino, Iop, Laura
core +4 more sources

