Results 1 to 10 of about 6,655 (118)

A chronological history of heart valve prostheses to offer perspectives of their limitations

Frontiers in Bioengineering and Biotechnology
Prosthetic heart valves (PHV) have been studied for around 70 years. They are the best alternative to save the life of patients with cardiac valve diseases. However, current PHVs may still cause significant disadvantages to patients.
Ana Luiza Resende Pires, Breno Valentim Nogueira   +1 more
exaly   +3 more sources

Tissue Engineering Heart Valves – a Review of More than Two Decades into Preclinical and Clinical Testing for Obtaining the Next Generation of Heart Valve Substitutes [PDF]

Romanian Journal of Cardiology, 2021
Well documented shortcomings of current heart valve substitutes – biological and mechanical prostheses make them imperfect choices for patients diagnosed with heart valve disease, in need for a cardiac valve replacement.
Dan SIMIONESCU, Marius Mihai HARPA, Agneta SIMIONESCU, Codrut OPRITA, Ionela MOVILEANU   +4 more
doaj   +1 more source

Evaluation of pliable bioresorbable, elastomeric aortic valve prostheses in sheep during 12 months post implantation

Communications Biology, 2023
Pliable microfibrous, bioresorbable elastomeric heart valve prostheses are investigated in search of sustainable heart valve replacement. These cell-free implants recruit cells and trigger tissue formation on the valves in situ. Our aim is to investigate
Annemijn Vis, Bente J. de Kort, Wojciech Szymczyk, Jan Willem van Rijswijk, Sylvia Dekker, Rob Driessen, Niels Wijkstra, Paul F. Gründeman, Hans W. M. Niessen, Henk M. Janssen, Serge H. M. Söntjens, Patricia Y. W. Dankers, Anthal I. P. M. Smits, Carlijn V. C. Bouten, Jolanda Kluin   +14 more
doaj   +1 more source

Recent progress in biomaterials for heart valve replacement: Structure, function, and biomimetic design

View, 2021
Heart diseases caused by structure and function degradation is troubling millions of people all over the world. With the extension of human lifespan, the demand for heart valve replacement is rapidly increasing.
Ziyu Shao, Tingting Tao, Hongfei Xu, Cen Chen, In‐Seop Lee, Sungmin Chung, Zhihui Dong, Weidong Li, Liang Ma, Hao Bai, Qianming Chen   +10 more
doaj   +1 more source

Developing the Tissue Engineered Heart Valve – a Descriptive Hemodynamic and Ultrasound in Vitro Characterization Study of Heart Valves in a Bioreactor [PDF]

Romanian Journal of Cardiology, 2021
The inherent limitations of current heart valve substitutes create the premise for the Tissue Engineered Heart Valve (TEHV), considered the perfect substitute. We aimed to compare in vitro hemodynamic performances of our TEHV, the conventional prosthetic
Ionela MOVILEANU, Dan Octavian NISTOR, Leslie SIERAD, Klara BRINZANIUC, Codrut OPRITA, Marius Mihai HARPA, Terezia PREDA, Ovidiu COTOI, Hussam AL HUSSEIN, Hamida AL HUSSEIN, Alexandru CHERTES, Horatiu SUCIU, Agneta SIMIONESCU, Dan SIMIONESCU   +13 more
doaj   +1 more source

Anticoagulation During Pregnancy with a Mechanical Pulmonary Valve: Patient and Medical Perspective

Cardiology and Therapy, 2022
This article discusses the challenges of supporting a successful pregnancy in a woman with multiple prosthetic heart valves and a complicated cardiac history, from both the patient and provider perspective.
Lauren Ledingham, Amanda Thiess, May Ling Mah   +2 more
doaj   +1 more source

Evaluation of the marker of hypercoagulability prothrombin fragment F 1+2 in patients with mechanical or biological heart valve prostheses

Arquivos Brasileiros de Cardiologia, 2002
OBJECTIVE: To investigate whether patients with heart valve prostheses and similar International Normalized Ratios (INR) have the same level of protection against thromboembolic events, that is, whether the anticoagulation intensity is related to the ...
Claudia Natália Ferreira, Lauro Mello Vieira, Luci Maria Sant'Ana Dusse, Carlos Faria Santos Amaral, William Antônio de Magalhães Esteves, Lúcia Maria Amorim Fenelon, Maria das Graças Carvalho   +6 more
doaj   +1 more source

Surgical techniques for aortic valve xenotransplantation

Journal of Cardiothoracic Surgery, 2021
Background Heart valve replacement in neonates and infants is one of the remaining unsolved problems in cardiac surgery because conventional valve prostheses do not grow with the children.
Jennie H. Kwon, Morgan Hill, Brielle Gerry, Steven W. Kubalak, Muhammad Mohiuddin, Minoo N. Kavarana, T. Konrad Rajab   +6 more
doaj   +1 more source

Clinical performance of decellularized heart valves versus standard tissue conduits: a systematic review and meta-analysis

Journal of Cardiothoracic Surgery, 2020
Background Valve replacement surgery is the definitive management strategy for patients with severe valvular disease. However, valvular conduits currently in clinical use are associated with significant limitations.
Steve W. F. R. Waqanivavalagi, Sameer Bhat, Marcus B. Ground, Paget F. Milsom, Jillian Cornish   +4 more
doaj   +1 more source

Antithrombotic Therapy in Patients with Prosthetic Heart Valves [PDF]

Libyan Journal of Medicine, 2009
Patients with mechanical valve prostheses require a lifelong anticoagulant treatment. The combined use of Warfarin and low-dose aspirin appears to reduce the risk of valve thrombosis and systemic embolism at a low risk of bleeding.
Mohamed HA
doaj