Results 11 to 20 of about 117,950 (235)

Next-generation tissue-engineered heart valves with repair, remodelling and regeneration capacity [PDF]

Nature Reviews Cardiology, 2020
Valvular heart disease is a major cause of morbidity and mortality worldwide. Surgical valve repair or replacement has been the standard of care for patients with valvular heart disease for many decades, but transcatheter heart valve therapy has ...
Lintas, Valentina; https://orcid.org/, Emmert, Maximilian Y; https://orcid.org/, Hoerstrup, Simon P; https://orcid.org/, Baaijens, Frank P T; https://orcid.org/, Falk, Volkmar; https://orcid.org/, Parker, Kevin Kit; https://orcid.org/, Motta, Sarah E, Loerakker, Sandra; https://orcid.org/, Fioretta, Emanuela S; https://orcid.org/   +8 more
core   +4 more sources

Artificial Heart Valves with Balanced Charged Networks Exhibiting Anti-Calcification Properties

ACS Applied Bio Materials, 2019
Currently, the only treatment for moderate and severe aortic valve calcification disease is valve replacement. The clinical use of bioprosthetic heart valves (BHVs) is limited because of device failure caused by structural degeneration, such as the ...
Mingxiao Hou, Feng Guo (180529), Mingxiao Hou (764716), Xing Zhang, Rui Yang (293531), Rui Yang, Yunen Liu (764712), Xing Zhang (11943), Yunen Liu, Kai Jiao (104304), Kai Jiao, Feng Guo   +11 more
core   +2 more sources

Heart Valve Prostheses in Pregnancy: Outcomes for Women and Their Infants [PDF]

Journal of the American Heart Association, 2014
Background As the prognosis of women with prosthetic heart valves improves, and increasing number are contemplating and undertaking pregnancy. Accurate knowledge of perinatal outcomes is essential, assisting counseling and guiding care.
Lawley, Claire M, Algert, Charles S, Ford, Jane B, Nippita, Tanya A, Figtree, Gemma A, Roberts, Christine L.   +5 more
openaire   +5 more sources

Multi-scale modelling of textile reinforced artificial tubular aortic heart valves

, 2016
Tissue engineered heart valves equivalent to the native aortic heart valves are in development as an alternative to available prostheses. To achieve sufficient mechanical stiffness for application in tissue engineered valves exposed to the systemic ...
Jockenhoevel, Stefan, Sodhani, Deepanshu, Stapleton, Scott E., Moreira, Ricardo, Mela, Petra, Jockenhövel, Stefan, Reese, Stefanie, Jockenhoevel, Stefan; id_orcid   +7 more
core   +2 more sources

Transcatheter tissue engineered heart valves

Expert Review of Medical Devices, 2014
Valvular heart disease represents a leading cause of mortality worldwide. Transcatheter heart valve replacement techniques have been recently introduced into the clinical routine expanding the treatment options for affected patients.
Weber, Benedikt, Falk, Volkmar, Hoerstrup, Simon P, Emmert, Maximilian Y   +3 more
core   +2 more sources

Facile engineering of interactive double network hydrogels for heart valve regeneration

Nature Communications
Regenerative heart valve prostheses are essential for treating valvular heart disease, which requested interactive materials that can adapt to the tissue remodeling process.
Jinsheng Li, Weihua Qiao, Yuqi Liu, Huiling Lei, Shuangshuang Wang, Yin Xu, Ying Zhou, Shuyu Wen, Zhuoran Yang, Wenyi Wan, Jiawei Shi, Nianguo Dong, Yuzhou Wu   +12 more
doaj   +2 more sources

Management of Life-Threatening Bleeding in Patients With Mechanical Heart Valves

Cureus, 2021
Valvular heart disease is common in the United States, with a number of patients undergoing valve replacement procedures every year. The two types of valve prostheses include mechanical and bioprosthetic valves.
S. Huda, S. Kahlown, M. Jilani, D. Chaudhuri   +3 more
semanticscholar   +1 more source

Recent progress in biomaterials for heart valve replacement: Structure, function, and biomimetic design

View, 2021
Heart diseases caused by structure and function degradation is troubling millions of people all over the world. With the extension of human lifespan, the demand for heart valve replacement is rapidly increasing.
Ziyu Shao, Tingting Tao, Hongfei Xu, Cen Chen, In‐Seop Lee, Sungmin Chung, Zhihui Dong, Weidong Li, Liang Ma, Hao Bai, Qianming Chen   +10 more
doaj   +1 more source

A New Nanocomposite Copolymer Based On Functionalised Graphene Oxide for Development of Heart Valves

Scientific Reports, 2020
Polymeric heart valves seem to be an attractive alternative to mechanical and biological prostheses as they are more durable, due to the superior properties of novel polymers, and have the biocompatibility and hemodynamics comparable to tissue ...
E. Ovcharenko, A. Seifalian, M. Rezvova, K. Klyshnikov, T. Glushkova, T. N. Akenteva, L. Antonova, E. Velikanova, Vera S. Chernonosova, G. Y. Shevelev, D. Shishkova, E. Krivkina, Yuliya A. Kudryavceva, A. Seifalian, L. Barbarash   +14 more
semanticscholar   +1 more source

Developing the Tissue Engineered Heart Valve – a Descriptive Hemodynamic and Ultrasound in Vitro Characterization Study of Heart Valves in a Bioreactor [PDF]

Romanian Journal of Cardiology, 2021
The inherent limitations of current heart valve substitutes create the premise for the Tissue Engineered Heart Valve (TEHV), considered the perfect substitute. We aimed to compare in vitro hemodynamic performances of our TEHV, the conventional prosthetic
Ionela MOVILEANU, Dan Octavian NISTOR, Leslie SIERAD, Klara BRINZANIUC, Codrut OPRITA, Marius Mihai HARPA, Terezia PREDA, Ovidiu COTOI, Hussam AL HUSSEIN, Hamida AL HUSSEIN, Alexandru CHERTES, Horatiu SUCIU, Agneta SIMIONESCU, Dan SIMIONESCU   +13 more
doaj   +1 more source