Evaluation of pliable bioresorbable, elastomeric aortic valve prostheses in sheep during 12 months post implantation [PDF]
Communications Biology, 2023 Pliable microfibrous, bioresorbable elastomeric heart valve prostheses are investigated in search of sustainable heart valve replacement. These cell-free implants recruit cells and trigger tissue formation on the valves in situ. Our aim is to investigate
Bouten, Carlijn V.C. +14 more
core +4 more sources
A chronological history of heart valve prostheses to offer perspectives of their limitations [PDF]
Frontiers in Bioengineering and BiotechnologyProsthetic heart valves (PHV) have been studied for around 70 years. They are the best alternative to save the life of patients with cardiac valve diseases. However, current PHVs may still cause significant disadvantages to patients.
Raquel Ahnert Aguiar Evangelista +3 more
doaj +3 more sources
Tissue Engineering Heart Valves – a Review of More than Two Decades into Preclinical and Clinical Testing for Obtaining the Next Generation of Heart Valve Substitutes [PDF]
Romanian Journal of Cardiology, 2021 Well documented shortcomings of current heart valve substitutes – biological and mechanical prostheses make them imperfect choices for patients diagnosed with heart valve disease, in need for a cardiac valve replacement.
Dan SIMIONESCU +4 more
doaj +2 more sources
Prediction of Turbulent Shear Stresses through Dysfunctional Bileaflet Mechanical Heart Valves using Computational Fluid Dynamics [PDF]
arXiv, 2018 There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease.
Gamage, Peshala T. +2 more
core +2 more sources
Journal of Cardiothoracic Surgery, 2020 Background Valve replacement surgery is the definitive management strategy for patients with severe valvular disease. However, valvular conduits currently in clinical use are associated with significant limitations.
Steve W. F. R. Waqanivavalagi +4 more
doaj +2 more sources
Evaluation of the marker of hypercoagulability prothrombin fragment F 1+2 in patients with mechanical or biological heart valve prostheses [PDF]
Arquivos Brasileiros de Cardiologia, 2002 OBJECTIVE: To investigate whether patients with heart valve prostheses and similar International Normalized Ratios (INR) have the same level of protection against thromboembolic events, that is, whether the anticoagulation intensity is related to the ...
Claudia Natália Ferreira +6 more
doaj +2 more sources
Comparative study of wall shear stress at the ascending aorta for different mechanical heart valve prostheses [PDF]
Journal of Biomechanical Engineering, 2019 An experimental study is reported which investigates the wall shear stress (WSS) distribution in a transparent model of the human aorta comparing a bileaflet mechanical heart valve (BMHV) with a trileaflet mechanical heart valve (TMHV) in physiological ...
Bruecker, C., Li, Q.
core +3 more sources
Next-generation tissue-engineered heart valves with repair, remodelling and regeneration capacity [PDF]
Nature Reviews Cardiology, 2021 Valvular heart disease is a major cause of morbidity and mortality worldwide. Surgical valve repair or replacement has been the standard of care for patients with valvular heart disease for many decades, but transcatheter heart valve therapy has ...
Baaijens, Frank P.T. +8 more
core +2 more sources
Comparative study of wall shear stress at the ascending aorta for different mechanical heart valve prostheses [PDF]
arXiv, 2018 An experimental study is reported which investigates the wall shear stress (WSS) distribution in a transparent model of the human aorta comparing a bileaflet mechanical heart valve (BMHV) with a trileaflet mechanical heart valve (TMHV) in physiological pulsatile flow.
Qianhui Li, Christoph Bruecker
arxiv +3 more sources
Natural biomaterials in the management of the aortic valve pathology. Biomedical and clinical aspects: A review [PDF]
Biomolecules & BiomedicineHeart valve diseases are a prevalent cardiovascular pathology worldwide, affecting nearly 2.5% of the population. Degenerative aortic stenosis is the most common form of heart valve disease.
Igor Mokryk +5 more
doaj +2 more sources