Results 51 to 60 of about 117,950 (235)

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

Estudo comparativo das características fluidodinâmicas de próteses valvulares biológicas de pericárdio bovino de perfil alto e baixo Comparative study of fluid dynamic characteristics in high and low biological prosthetic heart valves from bovine pericardium

Brazilian Journal of Cardiovascular Surgery, 1989
O comportamento fluidodinâmico e a vida útil média de uma prótese valvular cardíaca são características muito importantes na escolha do modelo de prótese a ser implantada em um determinado paciente.
Aron J. P Andrade, José F Biscegli, Denys E Nicolosi, Hernán C Gómez, J. Eduardo M. R Sousa   +4 more
doaj  

Advancements and Perspectives in the Bioprosthetic Heart Valve: A Comprehensive Review on Biomaterial Processing and Emerging Polymeric Materials

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Heart valve disease contributes to cardiovascular disease–associated death. Bioprosthetic heart valves have emerged as a preferred option for heart valve replacement due to their superior hemodynamic performance and reduced need for lifelong ...
Hanluo Li, Shenghua Li, Yalan Lei, Ming Sun, Chunlin Wu, Xueli Wang, Shiwen Xiong, Qing Wang, Sini Kang, Song Chen, Xiaoke Shang   +10 more
doaj   +1 more source

Preclinical Testing of Living Tissue-Engineered Heart Valves for Pediatric Patients, Challenges and Opportunities

Frontiers in Cardiovascular Medicine, 2021
Introduction: Pediatric patients with cardiac congenital diseases require heart valve implants that can grow with their natural somatic increase in size. Current artificial valves perform poorly in children and cannot grow; thus, living-tissue-engineered
Ionela Movileanu, Ionela Movileanu, Marius Harpa, Marius Harpa, Hussam Al Hussein, Hussam Al Hussein, Lucian Harceaga, Alexandru Chertes, Hamida Al Hussein, Georg Lutter, Thomas Puehler, Terezia Preda, Carmen Sircuta, Ovidiu Cotoi, Dan Nistor, Dan Nistor, Adrian Man, Bogdan Cordos, Radu Deac, Horatiu Suciu, Horatiu Suciu, Klara Brinzaniuc, Klara Brinzaniuc, Megan Casco, Leslie Sierad, Margarita Bruce, Dan Simionescu, Dan Simionescu, Agneta Simionescu   +28 more
doaj   +1 more source

Experimental MRI visible resonant prosthetic heart valves

, 2009
Artificial heart valves comprising metal can cause significant MR image artifacts due to the material (susceptibility artifact) and/or electromagnetic characteristics (RF artifact).
Immel, Erwin, Melzer, Andreas; id_orcid, Gilbert, F. J.   +2 more
core   +1 more source

Morphological and morphometric aspects of the equine aortic valve: New insights for comparative studies in mammals

The Anatomical Record, EarlyView.
Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira, Victoria Brondani de Oliveira, Carlos Eduardo Seyfert, Luciano de Morais‐Pinto   +3 more
wiley   +1 more source

Remoção cirúrgica de trombos em próteses valvulares mecânicas Surgical removal of thrombi in mechanical valvular prostheses

Brazilian Journal of Cardiovascular Surgery, 1993
É relatada a retirada cirúrgica de trombos em próteses mecânicas em dois pacientes, manobra rara e inédita em nossa Instituição. O primeiro paciente, do sexo masculino, de 19 anos de idade, com história de doença reumática na infância, tendo sido ...
Pablo M. A Pomerantzeff, Wilson Luiz da Silveira, Jorge Y Afiuni, Nana Ikari, Raquel Snitkowsky, Max Grinberg, Munir Ebaid, Miguel Barbero-Marcial, Geraldo Verginelli, A. D Jatene   +9 more
doaj  

Meshalkin National Medical Research Center

Российский кардиологический журнал, 2021
We present three cases of successful transatrial transcatheter valve-in-valve implantation in patients with bioprosthetic mitral valve dysfunction.
A. V. Bogachev-Prokofiev, R. M. Sharifulin, D. A. Astapov, M. A. Ovcharov, M. A. Ovchinnikova, S. O. Lavinyukov, A. V. Sapegin, A. V. Afanasyev, S. I. Zheleznev, V. M. Nazarov, A. M. Chernyavsky   +10 more
doaj   +1 more source

Bioengineered self-seeding heart valves

, 2012
ObjectiveMechanical and biological prostheses are used to replace damaged heart valves but are associated with significant morbidities. Although there is increased interest in bioengineering cell-seeded heart valve scaffolds, it is a time-consuming and ...
Lee, Sang-Jin, Sang-Jin Lee, J. Koudy Williams, Jordan, James E., Williams, J. Koudy, Raghavan, Devanathan, Atala, Anthony, James E. Jordan, Anthony Atala, Devanathan Raghavan, James J. Yoo, Yoo, James J.   +11 more
core   +1 more source

Macrophage‐targeted cerium‐tannic acid metal‐polyphenol framework nanoenzyme promotes in situ heart valves regeneration through adaptive immunomodulation

BMEMat, EarlyView.
A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song, Yunlong Wu, Xing Chen, Yafei Liu, Mengna Dong, Jiawei Shi, Xichi Wang, Nianguo Dong, Weihua Qiao, Qin Wang   +9 more
wiley   +1 more source