Results 121 to 130 of about 2,228,463 (350)
Multi-Planar Deep Segmentation Networks for Cardiac Substructures from MRI and CT [PDF]
Non-invasive detection of cardiovascular disorders from radiology scans requires quantitative image analysis of the heart and its substructures. There are well-established measurements that radiologists use for diseases assessment such as ejection fraction, volume of four chambers, and myocardium mass.
arxiv
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang+10 more
wiley +1 more source
Abstract Chromosome 1p36 deletion syndrome (1p36DS) is one of the most common terminal deletion syndromes (incidence between 1/5000 and 1/10,000 live births in the American population), due to a heterozygous deletion of part of the short arm of chromosome 1.
Clémence Jacquin+47 more
wiley +1 more source
The volumetric analysis of cardiac chambers and three-dimensional cardiac reconstruction during chicken embryo cardiogenesis [PDF]
Aim of this study was to quantitatively examine chicken heart’s parameters at the stage HH 29 and HH 35 (Hamburger and Hamilton, 1951). It was achieved by using three-dimensional (3D) reconstruction software to align multiple histological sections of the
Goodlett T.
doaj
Proteomics of Mouse Heart Ventricles Reveals Mitochondria and Metabolism as Major Targets of a Post-Infarction Short-Acting GLP1Ra-Therapy. [PDF]
de Freitas Germano J+10 more
europepmc +1 more source
Extravasation of Borrelia burgdorferi Across the Blood–Brain Barrier is an Extremely Rare Event
Lyme disease is caused by vascular dissemination of the bacteria Borrelia. In a 3D tissue‐engineered microvessel model, Borrelia extravasation across the blood–brain barrier is extremely rare, implying that neuroborreliosis is not caused via direct cytotoxicity.
Linus Wang+6 more
wiley +1 more source
Genetic and phenotypic spectrum in the NONO‐associated syndromic disorder
Abstract The non‐POU domain‐containing octamer‐binding (NONO) protein is involved in multiple steps of gene regulation such as RNA metabolism and DNA repair. Hemizygous pathogenic variants in the NONO gene were confirmed to cause a rare X‐linked syndromic disorder. Through our in‐house diagnostics and subsequent matchmaking, we identified six unrelated
Franziska Roessler+21 more
wiley +1 more source
Background and Objectives: Endurance exercise induces cardiac remodeling. Also, myh6 gene is affected by cardiac remodeling. This study was performed with the objective of determining the effect of endurance activity on cardiac myh6 gene expression ...
Mohammad Fathi
doaj
A rule-based method to model myocardial fiber orientation in cardiac biventricular geometries with outflow tracts [PDF]
Rule-based methods are often used for assigning fiber orientation to cardiac anatomical models. However, existing methods have been developed using data mostly from the left ventricle. As a consequence, fiber information obtained from rule-based methods often does not match histological data in other areas of the heart such as the right ventricle ...
arxiv
Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li+12 more
wiley +1 more source