Results 31 to 40 of about 81,103 (292)

Importance of the right ventricle in valvular heart disease [PDF]

open access: yesEuropean Heart Journal, 1996
The importance of the right ventricle as a determinant of clinical symptoms, exercise capacity, peri-operative survival and postoperative outcome has been underestimated for a long time. Right ventricular ejection fraction has been used as a measure of right ventricular function but has been found to be dependent on loading conditions, ventricular ...
Nagel, E, Stuber, M, Hess, O M
openaire   +5 more sources

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

6-Nitrodopamine Is the Most Potent Endogenous Positive Inotropic Agent in the Isolated Rat Heart

open access: yesLife, 2023
Background: 6-nitrodopamine released from rat isolated atria exerts positive chronotropic action, being more potent than noradrenaline, adrenaline, and dopamine.
José Britto-Júnior   +9 more
doaj   +1 more source

A piece of hammer in the right ventricle of the heart

open access: yesBMJ Case Reports, 2009
A 29-year-old male was referred to the surgery department with face injury after being hit with a small hammer fragment at work. Upon admission, he was slightly bleeding from the lacerated wound (size of 1×1 cm) in the maxillofacial region. Radiograph of the skull detected a small dense fragment in the region of injury (fig 1) and the patient was ...
Petr Widimsky   +5 more
openaire   +4 more sources

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

open access: yesAdvanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu   +6 more
wiley   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

open access: yesAdvanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García   +23 more
wiley   +1 more source

Impact of pulmonary hypertension on biventricular functions tissue doppler echocardiographic study

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2017
Background: Pulmonary hypertension (PH) essentially involves the right heart. Also left ventricular (LV) systolic and diastolic functions may be affected.
Mohamed Mahmoud   +2 more
doaj   +1 more source

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

open access: yesAdvanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er   +8 more
wiley   +1 more source

A tissue-engineered scale model of the heart ventricle [PDF]

open access: yesNature Biomedical Engineering, 2018
Laboratory studies of the heart use cell and tissue cultures to dissect heart function yet rely on animal models to measure pressure and volume dynamics. Here, we report tissue-engineered scale models of the human left ventricle, made of nanofibrous scaffolds that promote native-like anisotropic myocardial tissue genesis and chamber-level contractile ...
John F. Zimmerman   +28 more
openaire   +3 more sources

Highly Sensitive Cuffless Blood Pressure Monitoring with Selective Laser‐Sintered Liquid Metal Conductors

open access: yesAdvanced Functional Materials, EarlyView.
A soft, compact, and cuffless system for continuous blood pressure monitoring using laser‐sintered liquid metal conductors is developed. The stretchability and sensitivity of the device enable real‐time, non‐invasive tracking of blood pressure, including recovery after exercise. This wearable device offers a practical solution for managing hypertension
Jung Jae Park   +6 more
wiley   +1 more source

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