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Assessment of Burden of Partial Response to Standard Doses of Proton Pump Inhibitors in Patients with Clinically Diagnosed Gastroesophageal Reflux Disease: A Real-World Evidence Study in India. [PDF]

Drugs Real World Outcomes
Garje Y, Saikia R, Gupta S, Peri S, Sharma P, Dharmadhikari S, Satpathy A, Khandhedia C, Markandeywar N, Mane A, Mehta S, Joglekar S.   +11 more
europepmc   +1 more source

Response to Proton-Pump Inhibitors Therapy in Pediatric Patients With Eosinophilic Esophagitis in Bogotá, Colombia. [PDF]

Can J Gastroenterol Hepatol
Rodríguez López AE, Vera Chamorro JF, Carias Domínguez AM, Pinilla Roncancio MV, López Panqueva RDP, Montaño Rozo GA.   +5 more
europepmc   +1 more source

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Psychological processes, not physiological parameters, are most important contributors to symptom severity in patients with refractory heartburn/regurgitation symptoms.

Gastroenterology, 2023
BACKGROUND AND AIMS Physiological and psychological factors have been shown to influence esophageal symptom reporting. We aim to evaluate which of these factors are associated with three reflux symptom severity outcomes (Total, Heartburn, and Sleep ...
Livia Guadagnoli, A. Geeraerts, H. Geysen, A. Pauwels, T. Vanuytsel, J. Tack, L. Van Oudenhove   +6 more
semanticscholar   +1 more source

How safe are heartburn medications and who should use them?

Expert Opinion on Drug Safety, 2023
Introduction Heartburn is a frequent symptom occurring in daily clinical practice and is mainly associated with gastroesophageal reflux disease (GERD).
V. Savarino, E. Marabotto, P. Zentilin, N. de Bortoli, Pierfrancesco Visaggi, M. Furnari, G. Bodini, E. Giannini, E. Savarino   +8 more
semanticscholar   +1 more source

Overlap of heartburn, functional dyspepsia, and irritable bowel syndrome in a population sample: Prevalence, temporal stability, and associated comorbidities

Neurogastroenterology and Motility, 2022
Co‐occurring (overlapping) irritable bowel syndrome (IBS), functional dyspepsia (FD), and heartburn has been observed. However, whether it is a distinct entity has not been established, nor what clinical, demographic, lifestyle, and psychological traits ...
Michael P. Jones, A. Shah, M. Walker, N. Koloski, G. Holtmann, N. Talley   +5 more
semanticscholar   +1 more source

Applying Lyon Consensus criteria in the work‐up of patients with proton pump inhibitory‐refractory heartburn

Alimentary Pharmacology and Therapeutics, 2022
A hierarchical approach for gastro‐oesophageal reflux disease (GERD) diagnosis by impedance‐pH monitoring was proposed by the Lyon Consensus, based on acid exposure time (AET) and supportive impedance metrics.
M. Frazzoni, L. Frazzoni, M. Ribolsi, N. Bortoli, S. Tolone, S. Russo, R. Conigliaro, R. Penagini, L. Fuccio, R. Zagari, E. Savarino   +10 more
semanticscholar   +1 more source

Recent insights on functional heartburn and reflux hypersensitivity

Current Opinion in Gastroenterology, 2022
Purpose of review Rome IV experts have proposed that gastroesophageal reflux disease (GERD) should be diagnosed only in patients with abnormal esophageal acid exposure, and that reflux hypersensitivity (RH) and functional heartburn (FH) both should be ...
E. Savarino, E. Marabotto, V. Savarino
semanticscholar   +1 more source

AGA Clinical Practice Update on Functional Heartburn: Expert Review.

Gastroenterology, 2020
Best Practice Advice 1 A diagnosis of functional heartburn should be considered when retrosternal burning pain or discomfort persists despite maximal (double-dose) proton pump inhibitor (PPI) therapy taken appropriately before meals during a 3-month ...
R. Fass, F. Zerbib, C. Gyawali
semanticscholar   +1 more source

Functional heartburn

Current Treatment Options in Gastroenterology, 2005
Functional heartburn (FH) is a common disorder that accounts for 30% to 50% of the patients with nonerosive reflux disease. FH is composed from a heterogeneous group of patients. They primarily include the hypersensitive and the nonacid sensitive esophagus.
Ram, Dickman, Ronnie, Fass
openaire   +2 more sources

Functional heartburn

Current Treatment Options in Gastroenterology, 2002
Functional heartburn is defined as the presence of a retrosternal burning sensation in the absence of pathologic gastroesophageal reflux. The underlying pathophysiology seems to be heterogeneous. In a subset of patients, esophageal hypersensitivity to physiologic esophageal acid exposure is involved, and this is likely to respond to intensive ...
Jan, Tack, Jozef, Janssens
openaire   +2 more sources