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Functional heartburn

Current Treatment Options in Gastroenterology, 2005
Functional heartburn (FH) is a common disorder that accounts for 30% to 50% of the patients with nonerosive reflux disease. FH is composed from a heterogeneous group of patients. They primarily include the hypersensitive and the nonacid sensitive esophagus.
Ram, Dickman, Ronnie, Fass
openaire   +2 more sources

Overlap of functional heartburn and reflux hypersensitivity with proven gastroesophageal reflux disease

Neurogastroenterology and Motility, 2020
When esophageal acid exposure time (AET) is physiologic, ROME IV stratifies functional esophageal disorders into functional heartburn (FH, with negative reflux‐symptom association) and reflux hypersensitivity (RH, with positive reflux‐symptom association)
A. Rengarajan   +3 more
semanticscholar   +1 more source

Functional heartburn

Current Treatment Options in Gastroenterology, 2002
Functional heartburn is defined as the presence of a retrosternal burning sensation in the absence of pathologic gastroesophageal reflux. The underlying pathophysiology seems to be heterogeneous. In a subset of patients, esophageal hypersensitivity to physiologic esophageal acid exposure is involved, and this is likely to respond to intensive ...
Jan, Tack, Jozef, Janssens
openaire   +2 more sources

Refractory Gastroesophageal Reflux Disease and Functional Heartburn.

Gastrointestinal Endoscopy Clinics of North America, 2020
This report discusses the potential mechanisms that might underlie refractory GERD and functional heartburn, and how to distinguish among those mechanisms using a systematic evaluation that includes careful medical history, endoscopy with esophageal ...
S. Spechler
semanticscholar   +1 more source

HEARTBURN

Journal of the American Medical Association, 1949
All physicians encounter patients who have symptoms that are difficult to treat because the mechanisms which produce them are poorly understood. Gastroenterologists deal with a number of such symptoms, among which may be listed not only the many varieties of abdominal pain but also such complaints as belching, flatulence, malodorous breath, a bad taste
H J, TUMEN, E M, COHN
openaire   +2 more sources

New York clinical trial quietly tests heartburn remedy against coronavirus

, 2020
The fast-growing list of possible treatments for the novel coronavirus includes an unlikely candidate: famotidine, the active compound in the over-the-counter heartburn drug Pepcid On 7 April, the first COVID-19 patients at Northwell Health in the New ...
B. Borrell
semanticscholar   +1 more source

BEHAVIORAL THERAPY FOR FUNCTIONAL HEARTBURN: Recommendation Statements.

Clinical Gastroenterology and Hepatology
BACKGROUND & AIMS Brain-gut behavior therapies (BGBT) are increasingly recognized as effective therapeutic interventions for functional heartburn. However, recommendations regarding candidacy for treatment, initial treatment selection, and navigating ...
Livia Guadagnoli   +15 more
semanticscholar   +1 more source

The infusion of menthol into the esophagus evokes cold sensations in healthy subjects but induces heartburn in patients with gastroesophageal reflux disease (GERD).

Diseases of the esophagus, 2019
Recent studies in animal models have reported that some afferent fibers innervating the esophagus express the cold receptor TRPM8. In the somatosensory system the stimulation of TRPM8 leads to cold sensations and in certain circumstances alleviates pain.
P. Bánovčin   +5 more
semanticscholar   +1 more source

Heartburn

Nutrition Today, 2018
Heartburn (pyrosis) can be defined as a burning sensation behind the sternum. Heartburn is typically caused by stomach acid that has refluxed back into the esophagus through the lower esophageal sphincter (which is normally closed except when swallowing). Most people who experience heartburn actually produce normal amounts of stomach acid, so heartburn
openaire   +2 more sources

Mechanisms of heartburn

Nature Clinical Practice Gastroenterology & Hepatology, 2008
Heartburn is a typical symptom of GERD. The spectrum of diseases associated with GERD includes reflux esophagitis, Barrett's esophagus and nonerosive reflux disease (NERD). Although acid reflux is the classic cause of heartburn in patients with erosive esophagitis, the relationship between acid and heartburn is far from clear, especially in patients ...
Daphne, Ang, Daniel, Sifrim, Jan, Tack
openaire   +2 more sources

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