Results 41 to 50 of about 10,972 (207)

Population Pharmacokinetics of Sildenafil in Dogs With Naturally Occurring Pulmonary Hypertension

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The pharmacokinetics of sildenafil are ill‐defined in dogs with naturally occurring pulmonary hypertension (PH). Because the plasma concentrations of sildenafil have not been reported for dogs with this disease, this study aimed to describe the population pharmacokinetics of sildenafil in a sample of dogs with PH. Twenty client‐owned dogs with
Mariko Yata, Teresa C. DeFrancesco, John D. Bonagura, Mark G. Papich   +3 more
wiley   +1 more source

Evaluation of feline heartworm disease based on gross necropsy, serology, pulmonary histopathology, and radiographic evidence in adult shelter cats in northeastern Alabama

Parasites & Vectors
Background : Veterinary knowledge regarding feline heartworm has been increasing significantly over the past two decades. Necropsy surveys of shelter cats have shown feline adult heartworm infection prevalence to be 5–20% of the rate in unprotected dogs;
C. Thomas Nelson, Calvin M. Johnson
doaj   +1 more source

Perceptions of Medications and Supplements by U.S. Dog‐Interested Members of the Public and Final‐Year Veterinary Students

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Veterinary graduates must be prepared to educate clients about medications and supplements. We surveyed 1955 Dog Aging Project newsletter recipients and 40 final‐year veterinary students at Texas A&M College of Veterinary Medicine and Biomedical Sciences on their perceptions about medications and supplements. Respondents indicated whether each
Sidonie T. Gallinger, Johanna C. Heseltine, Kate Illing, Virginia R. Fajt, Dog Aging Project Consortium, Joshua M. Akey, Brooke Benton, Elhanan Borenstein, Marta G. Castelhano, Amanda E. Coleman, Kate E. Creevy, Kyle Crowder, Matthew D. Dunbar, Virginia R. Fajt, Annette L. Fitzpatrick, Unity Jeffery, Erica C. Jonlin, Matt Kaeberlein, Elinor K. Karlsson, Kathleen F. Kerr, Jonathan M. Levine, Jing Ma, Robyn L. McClelland, Daniel E. L. Promislow, Audrey Ruple, Stephen M. Schwartz, Sandi Shrager, Noah Snyder‐Mackler, M. Katherine Tolbert, Silvan R. Urfer, Benjamin S. Wilfond, Kate E. Creevy   +31 more
wiley   +1 more source

Use of Slow-Release Injectable Moxidectin for Treatment of Dirofilaria immitis Infection During Pregnancy

Frontiers in Veterinary Science, 2020
Canine heartworm disease is a life-threatening disease caused by Dirofilaria immitis and is prevalent in Brazil. The standard drug for its treatment, melarsomine dihydrochloride, is a fast-killing organic arsenical chemotherapeutic agent not approved in ...
Bruno Alberigi, Celeste da Silva Freitas de Souza, Julio Israel Fernandes, Alexandre Merlo, Norma Labarthe   +4 more
doaj   +1 more source

Assessment of Platelet Storage Lesions, Viability, and Function in Canine Platelet Concentrate Units Stored at 4°C for 14 Days

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To assess platelet function, storage lesion development, and bacterial contamination in canine platelet concentrate (PC) units stored at 4°C for 14 days. Design Prospective, in vitro experimental study. Setting University teaching hospital. Animals Six units of canine PC.
Kate S. Farrell, Steven E. Epstein, Nghi Nguyen, Ronald H. L. Li   +3 more
wiley   +1 more source

A comparative analysis of heartworm medication use patterns for dogs that also receive ectoparasiticides

Parasites & Vectors, 2018
Background Heartworm medications and many oral or topical flea and tick products are provided as monthly doses while a newer oral flea/tick product, fluralaner (BRAVECTO® Chew), is re-dosed at a 12-week interval. This study focused on whether there was a
Robert Lavan, Kathleen Heaney, Srinivasan Rajagopalan Vaduvoor, Kaan Tunceli   +3 more
doaj   +1 more source

Presence of the ABCB1 (MDR1) deletion mutation causing ivermectin hypersensitivity in certain dog breeds in Belgium [PDF]

, 2009
Hypersensitivity to ivermectin and certain other drugs in Collies and related breeds is caused by a 4-base pair deletion mutation in the ABCB1 gene, better known as the MDR1 gene, encoding P-glycoprotein.
Daminet, Sylvie, Erkens, Tim, Gommeren, Kris, Lampo, Evelyne, Peelman, Luc, Rogiers, Carolien, Van den Broeke, Alice, Van Poucke, Mario, Van Zeveren, Alex, Vander Donckt, Dominique   +9 more
core   +2 more sources

Small RNAs and extracellular vesicles in filarial nematodes: from nematode development to diagnostics [PDF]

, 2016
Parasitic nematodes have evolved sophisticated mechanisms to communicate with their hosts in order to survive and successfully establish an infection. The transfer of RNA within extracellular vesicles (EVs) has recently been described as a mechanism that
Babayan, S.A., Buck, A.H., Quintana, J.F.   +2 more
core   +3 more sources

Echocardiographic Evaluation of the Right Ventricular Thickness, Myocardial Visualization, and Fractional Area Change: The Impact of Contrast Agent and Transducer Selection

Veterinary Radiology &Ultrasound, Volume 67, Issue 2, March 2026.
ABSTRACT Accurate assessment of right ventricular wall thickness, myocardial visualization, and chamber dimensions is crucial in veterinary cardiology but remains understudied in dogs. This prospective observational study evaluated 10 healthy beagle dogs to compare three echocardiographic approaches for assessing right ventricular parameters: sector ...
Yeonju Park, Suyeon Yoon, Sumin Han, Jihye Shin, Minhyung Kim, Seungjo Park   +5 more
wiley   +1 more source

Prevalence, gross and histopathological findings in the lungs of suspected heartworm infected cats in the Klang Valley, Malaysia [PDF]

, 2012
Feline heartworm disease is a potentially life-threatening disease of cats that most commonly manifests as heartworm-associated respiratory disease (HARD).
Jalil, Julida, Mohamed Mustapha, Noordin, Watanabe, Malaika   +2 more
core