Results 91 to 100 of about 11,230,134 (287)

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

open access: yesAdvanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu   +5 more
wiley   +1 more source

Heat-related illness in individuals using psychiatric medication : 2017.

open access: yes, 2017
Brochure; intended to be printed off on one sheet, front and back, and folded in thirds.Common psychotropic medications that may impair the heat response -- Medical conditions and medications affect body temperature -- Medication list -- Heat stroke ...

core  

Heat-Related Illness versus All Hospitalizations Rates, Summer 2001–2010.

open access: yes, 2016
The dotted line represents the rate of all hospitalizations during the study time period which remained approximately level over time. The solid line represents heat-related illness hospitalizations which although varied by year have steadily increased ...
Peter J. Marcotullio (2216752)   +5 more
core   +1 more source

Highly‐Time‐Resolved Measurements of Tryptophan's Distribution and Homeostatic Regulation in Live, Intact Animals

open access: yesAdvanced Science, EarlyView.
Using a novel, aptamer‐based biosensor, here we have performed 20‐s‐resolved, in situ measurements of plasma‐free tryptophan in the jugular veins of live rats (blue). This unprecedented time‐resolution provides insights into the regulation of tryptophan metabolism in live, intact animals.
Yuyang Wu   +7 more
wiley   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

open access: yesAdvanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang   +10 more
wiley   +1 more source

Heat-related illness in individuals using psychiatric medication : 2018.

open access: yes, 2018
Brochure; intended to be printed off on one sheet, front and back, and folded in thirds.Common psychotropic medications that may impair the heat response -- Medical conditions and medications affect body temperature -- Medication list -- Heat stroke ...

core  

Heat strain, hydration status, and symptoms of heat illness in surface mine workers [PDF]

open access: yes, 2011
The aim of the research program was to evaluate the heat strain, hydration status, and heat illness symptoms experienced by surface mine workers. An initial investigation involved 91 surface miners completing a heat stress questionnaire; assessing the ...
Hunt, Andrew Philip
core  

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

open access: yesAdvanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan   +7 more
wiley   +1 more source

Job Anxiety, Work-Related Psychological Illness and Workplace Performance [PDF]

open access: yes
This paper uses matched employee-employer data from the British Workplace Employment Relations Survey (WERS) 2004 to examine the determinants of employee job anxiety and work-related psychological illness.
Jones, Melanie K.   +2 more
core  

Females exposed to 24 hours of sleep deprivation do not experience greater physiological strain, but do perceive heat illness symptoms more severely, during exercise-heat stress [PDF]

open access: yes, 2017
Purpose: There is limited and inconclusive evidence surrounding the physiological and perceptual responses to heat stress while sleep deprived, especially for females.
Maxwell, Neil S   +27 more
core   +1 more source

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