Results 81 to 90 of about 11,230,134 (287)

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Heat stress Regulations and standards: The key to preventing heat-related illness

open access: yesطب کار, 2017
Introduction: One ways to prevent heat stress illness and protect workers is regional and national legislation and international standards about heat stress.
Mehdi Asghari   +5 more
doaj  

Workers’ perceptions of climate change related extreme heat exposure in South Australia: a cross-sectional survey

open access: yesBMC Public Health, 2016
Background Occupational exposure to extreme heat without sufficient protection may not only increase the risk of heat-related illnesses and injuries but also compromise economic productivity.
Jianjun Xiang   +3 more
doaj   +1 more source

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

open access: yesAdvanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou   +11 more
wiley   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

open access: yesAdvanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan   +16 more
wiley   +1 more source

Correlated Polymer‐Proton Hopping Enables Water‐Independent Fast Proton Transport in Poly(Ionic Liquid) Membranes

open access: yesAdvanced Science, EarlyView.
A polymer chain in motion: backbone, ring, and counterion dynamics interlock across timescales to relay protons through poly(ionic liquid) membranes. ABSTRACT Polymer electrolyte membranes composed of ionic liquids (IL), capable of conducting protons efficiently at elevated temperatures, without external humidification, could transform fuel cell ...
Keenan Smith   +11 more
wiley   +1 more source

Heat related illness in palm oil mill workers under heat stress [PDF]

open access: yes, 2014
Background: Occupational heat stress is a one of the major issues in tropical countries such as Malaysia which affects workers' health and performance.
Mohd Tamrin, Shamsul Bahri   +2 more
core   +1 more source

Avoiding heat-related illness

open access: yes, 2017
Tips for avoiding heat-related illness during the solar eclipse.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Evaluation of a Novel Syndromic Surveillance Query for Heat-Related Illness Using Hospital Data From Maricopa County, Arizona, 2015

open access: yes, 2017
Objectives: We evaluated a novel syndromic surveillance query, developed by the Council of State and Territorial Epidemiologists (CSTE) Heat Syndrome Workgroup, for identifying heat-related illness cases in near real time, using emergency department and ...
Jessica R. White   +5 more
core   +1 more source

Relationships between maximum temperature and heat-related illness across North Carolina, USA [PDF]

open access: yes, 2016
Heat kills more people than any other weather-related event in the USA, resulting in hundreds of fatalities each year. In North Carolina, heat-related illness accounts for over 2,000 yearly emergency department admissions.
Sugg, Margaret M.   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy