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Heat Shock Proteins and Ferroptosis

Frontiers in Cell and Developmental Biology, 2022
Ferroptosis is a new form of regulatory cell death named by Dixon in 2012, which is characterized by the accumulation of lipid peroxides and iron ions. Molecular chaperones are a class of evolutionarily conserved proteins in the cytoplasm. They recognize
Ying Liu, Ying Liu, Ying Liu, Ying Liu, Lin Zhou, Lin Zhou, Lin Zhou, Lin Zhou, Yunfei Xu, Yunfei Xu, Yunfei Xu, Yunfei Xu, Kexin Li, Kexin Li, Kexin Li, Kexin Li, Yao Zhao, Yao Zhao, Yao Zhao, Yao Zhao, Haoduo Qiao, Haoduo Qiao, Haoduo Qiao, Haoduo Qiao, Qing Xu, Qing Xu, Qing Xu, Qing Xu, Jie Zhao   +28 more
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Heat-Shock Proteins in Neuroinflammation

Frontiers in Pharmacology, 2019
The heat-shock response, one of the main pro-survival mechanisms of a living organism, has evolved as the biochemical response of cells to cope with heat stress.
Brigitta Dukay, Brigitta Dukay, Bálint Csoboz, Melinda E. Tóth   +3 more
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Heat Shock Proteins as Immunomodulants

Molecules, 2018
Heat shock proteins (Hsps) are conserved molecules whose main role is to facilitate folding of other proteins. Most Hsps are generally stress-inducible as they play a particularly important cytoprotective role in cells exposed to stressful conditions ...
Tawanda Zininga, Lebogang Ramatsui, Addmore Shonhai   +2 more
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Heat Shock Proteins in Behçet Syndrome [PDF]

Balkan Medical Journal, 2023
Behçet syndrome (BS) is a systemic vasculitis of unknown etiology that affects the skin, mucosa, joints, eyes, central nervous system, gastrointestinal system, arteries, and veins.
Aslı Kıymet Kireçtepe Aydın, Gülen Hatemi   +1 more
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Two sides of the same coin: heat shock proteins as biomarkers and therapeutic targets for some complex diseases [PDF]

Frontiers in Molecular Biosciences
Heat shock proteins are molecular chaperones that play crucial roles in the folding and unfolding of complex polypeptides within the cellular system. These molecules are involved in various processes, including vesicular transport, prevention of protein ...
Xolani Henry Makhoba
doaj   +2 more sources

Barcoding heat shock proteins to human diseases: looking beyond the heat shock response

Disease Models & Mechanisms, 2014
There are numerous human diseases that are associated with protein misfolding and the formation of toxic protein aggregates. Activating the heat shock response (HSR) – and thus generally restoring the disturbed protein homeostasis associated with such ...
Vaishali Kakkar, Melanie Meister-Broekema, Melania Minoia, Serena Carra, Harm H. Kampinga   +4 more
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Heat shock proteins: Biological functions, pathological roles, and therapeutic opportunities

MedComm, 2022
The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect cells from stresses.
Chen Hu, Jing Yang, Z. Qi, Hong Wu, Bei-lei Wang, F. Zou, Husheng Mei, Jing Liu, Wen-chao Wang, Qingsong Liu   +9 more
semanticscholar   +1 more source

Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth

Scientific Reports, 2021
Heat shock proteins are involved in the response to stress including activation of the immune response. Elevated circulating heat shock proteins are associated with spontaneous preterm birth (SPTB).
Johanna M. Huusko, Heli Tiensuu, Antti M. Haapalainen, Anu Pasanen, Pinja Tissarinen, Minna K. Karjalainen, Ge Zhang, Kaare Christensen, Kelli K. Ryckman, Bo Jacobsson, Jeffrey C. Murray, Stephen F. Kingsmore, Mikko Hallman, Louis J. Muglia, Mika Rämet   +14 more
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Eukaryotic DNAJ/K Database: A Comprehensive Phylogenomic Analysis Platform for the DNAJ/K Family [PDF]

Genomics & Informatics, 2013
Proteins in DNAJ/K families are ubiquitous, from prokaryotes to eukaryotes, and function as molecular chaperones. For systematic phylogenomics of the DNAJ/K families, we developed the Eukaryotic DNAJ/K Database (EDD).
Kyeongchae Cheong, Jaehyuk Choi, Jaeyoung Choi, Jongsun Park, Suwang Jang, Yong-Hwan Lee   +5 more
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Archaebacterial heat-shock proteins [PDF]

The EMBO Journal, 1984
The response to heat shock was examined in seven archaebacterial strains from the genus Halobacterium. Upon heat shock each strain preferentially synthesized a limited number of proteins which fell into three narrow mol. wt. ranges. Further examination of the heat-shock response in H.
C J, Daniels, A H, McKee, W F, Doolittle
openaire   +2 more sources