Results 181 to 190 of about 216,912 (262)

Disulfide Bond–Modified Proteomics Reveals the Effects of Riboflavin on Protein Folding Dynamics

Animal Research and One Health, EarlyView.
Riboflavin deficiency impairs oxidative protein folding, causing ER misfolded protein accumulation, CHOP activation, and apoptosis, revealing a role of riboflavin in proteostasis. ABSTRACT Riboflavin is a crucial micronutrient essential for maintaining cellular homeostasis, acting as an important precursor for flavoproteins that utilize flavin ...
Bo Zhang, Shuisheng Hou, Jing Tang
wiley   +1 more source

Implication of Two Small Heat Shock Proteins in the Thermotolerance of <i>Bradysia odoriphaga</i> (Diptera: Sciaridae) Yang et Zhang. [PDF]

Insects
Cheng J, Zheng H, Feng S, Cao W, Wu Q, Song J.   +5 more
europepmc   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura B. Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore   +19 more
wiley   +1 more source

A Study on the Temperature-Dependent Behavior of Small Heat Shock Proteins from Methanogens. [PDF]

Int J Mol Sci
Kurokawa N, Ogawa M, Midorikawa R, Kanno A, Naka W, Noguchi K, Morishima K, Inoue R, Sugiyama M, Yohda M.   +9 more
europepmc   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Modulation of Heat Shock Proteins Levels in Health and Disease: An Integrated Perspective in Diagnostics and Therapy. [PDF]

Cells
Mikhailova E, Sokolenko A, Combs SE, Shevtsov M.   +3 more
europepmc   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Evaluation of serum levels of heat shock protein 70 in patients with psoriasis in Basra, Iraq

Menopause Review
Wafaa Taresh Adday, Abdulkader A. Al-Shakour, Samer A. Taher, Wafaa Taresh   +3 more
doaj   +1 more source

The Role of <i>Helicobacter pylori</i> Heat Shock Proteins in Gastric Diseases' Pathogenesis. [PDF]

Int J Mol Sci
Manna OM, Caruso Bavisotto C, Gratie MI, Damiani P, Tomasello G, Cappello F.   +5 more
europepmc   +1 more source

Heat Shock Protein and Immunity

Japanese journal of leprosy, 1995
openaire   +3 more sources