Results 51 to 60 of about 622,108 (337)

Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach

International Journal of Molecular Sciences, 2017
Heat shock proteins (HSPs) are a large family of chaperones that are involved in protein folding and maturation of a variety of “client” proteins protecting them from degradation, oxidative stress, hypoxia, and thermal stress. Hence, they are significant
S. Chatterjee, T. Burns
semanticscholar   +1 more source

Proteolysis in the Escherichia coli heat shock response: a player at many levels [PDF]

, 2011
Proteolysis is a fundamental process used by all forms of life to maintain homeostasis, as well as to remodel the proteome following environmental changes.
Baker, Tania, Meyer, Anne S.
core   +1 more source

Changes in the transcriptome of morula-stage bovine embryos caused by heat shock: relationship to developmental acquisition of thermotolerance

Reproductive Biology and Endocrinology, 2013
Background While initially sensitive to heat shock, the bovine embryo gains thermal resistance as it progresses through development so that physiological heat shock has little effect on development to the blastocyst stage by Day 5 after insemination ...
Sakatani Miki, Bonilla Luciano, Dobbs Kyle B, Block Jeremy, Ozawa Manabu, Shanker Savita, Yao JiQiang, Hansen Peter J   +7 more
doaj   +1 more source

CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin.

Immunity, 2001
Sreyashi Basu, R. Binder, T. Ramalingam, P. Srivastava   +3 more
semanticscholar   +3 more sources

Small heat shock proteins: Simplicity meets complexity

Journal of Biological Chemistry, 2018
Small heat shock proteins (sHsps) are a ubiquitous and ancient family of ATP-independent molecular chaperones. A key characteristic of sHsps is that they exist in ensembles of iso-energetic oligomeric species differing in size.
M. Haslbeck, S. Weinkauf, J. Buchner
semanticscholar   +1 more source

Hsp70 in mitochondrial biogenesis [PDF]

, 1994
The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
A. Tzagoloff, A. Tzagoloff, A.J. Caplan, A.J. Caplan, B.D. Gambill, B.S. Glick, C.K. Suzuki, D. Ang, D. M. Cyr, D.M. Cyr, D.M. Cyr, D.M. Cyr, D.M. Cyr, D.P. Atencio, E. Ikeda, E. Kutejová, E.A. Craig, E.A. Craig, F.-U. Hartl, G.S.P. Groot, H.R.B. Pelham, J. Ostermann, J. Rassow, J.F. Dice, J.P. Hendrick, K. Liberek, L. Dyck van, M. Eilers, M. Kiebler, M. Schleyer, M.-J. Gething, M.Y. Cheng, N. Rowley, N. Wang, P. Borst, P. Terpstra, P.-J. Kang, R. A. Stuart, R.A. Stuart, R.A. Stuart, R.B. Deshaies, R.G. Hadikusumo, R.J. Nelson, R.P. Beckman, S. Lindquist, S. Rospert, S.T. Hwang, T. Langer, U.C. Manning-Krieg, W. Neupert, W. Neupert, W. Voos, W.J. Chirico, Z. Xia   +53 more
core   +1 more source

Functions and Therapeutic Use of Heat Shock Proteins in Hepatocellular Carcinoma

Livers
Heat shock proteins are intracellular proteins expressed in prokaryotes and eukaryotes that help protect the cell from stress. They play an important role in regulating cell cycle and cell death, work as molecular chaperons during the folding of newly ...
Ramakrushna Paul, Smriti Shreya, Shweta Pandey, Srishti Shriya, Aya Abou Hammoud, Christophe F. Grosset, Buddhi Prakash Jain   +6 more
doaj   +1 more source

The Emerging Role of Heat Shock Factor 1 (HSF1) and Heat Shock Proteins (HSPs) in Ferroptosis

Pathophysiology, 2023
Cells employ a well-preserved physiological stress response mechanism, termed the heat shock response, to activate a certain type of molecular chaperone called heat shock proteins (HSPs).
Iman Aolymat, Ma’mon M. Hatmal, Amin N. Olaimat   +2 more
doaj   +1 more source

Heat Shock Response and Heat Shock Proteins: Current Understanding and Future Opportunities in Human Diseases

International Journal of Molecular Sciences
The heat shock response is an evolutionarily conserved mechanism that protects cells or organisms from the harmful effects of various stressors such as heat, chemicals toxins, UV radiation, and oxidizing agents.
Manish Kumar Singh, Yoonhwa Shin, Songhyun Ju, Sunhee Han, W. Choe, Kyung-Sik Yoon, Sung Soo Kim, I. Kang   +7 more
semanticscholar   +1 more source

Heat Shock Proteins Regulatory Role in Neurodevelopment

Frontiers in Neuroscience, 2018
Heat shock proteins (Hsps) are a large family of molecular chaperones that are well-known for their roles in protein maturation, re-folding and degradation.
David J. Miller, P. Fort
semanticscholar   +1 more source