Results 91 to 100 of about 5,291,187 (301)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

High thermal power density heat transfer apparatus providing electrical isolation at high temperature using heat pipes [PDF]

open access: yes, 1985
This invention is directed to transferring heat from an extremely high temperature source to an electrically isolated lower temperature receiver. The invention is particularly concerned with supplying thermal power to a thermionic converter from a ...
Morris, J. F.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Influence of Heat Input Ratio on Electrical Power Output of a Dual-Core Travelling-Wave Thermoacoustic Engine [PDF]

open access: yes
This paper presents an analytical and experimental investigation of an electricity generator that employs a two-stage looped tube travellin -wave thermoacoustic prime-mover to deliver acoustic power from heat energy, a loudspeaker to extract electricity ...
Hann, D.   +3 more
core  

A method for predicting interfacial freezing of a liquid flowing over a cold surface [PDF]

open access: yes, 1969
Instantaneous thickness of a frozen layer is a function of specific heat, heat of fusion, temperatures, the frozen layer thickness at equilibrium, the thermal conductivity, and heat transfer coefficient.
Savino, J. M., Siegel, R.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The environmental impact of refuse derived fuel co-combustion with lignite

open access: yesMATEC Web of Conferences, 2018
Legal regulations on waste disposal require waste producers to limit landfilling and to find different ways of waste management, the preferred methods being recycling of material and energy potential.
Krawczyk Piotr   +2 more
doaj   +1 more source

Sorption and desorption isotherms of celery roots [PDF]

open access: yesBIO Web of Conferences
An experimental study for determining the wet basis equilibrium moisture content in celery root (Apium graveolens) was conducted. Empirical equations describing the isotherms of sorption and desorption of the product at a temperature of 20°C were ...
Georgieva Mariya   +3 more
doaj   +1 more source

Cooling system for high speed aircraft [PDF]

open access: yes, 1981
The system eliminates the necessity of shielding an aircraft airframe constructed of material such as aluminum. Cooling is accomplished by passing a coolant through the aircraft airframe, the coolant acting as a carrier to remove heat from the airframe ...
Lawing, P. L., Pagel, L. L.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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