Results 71 to 80 of about 1,130,575 (394)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

R134a flow boiling heat transfer in small diameter tubes [PDF]

, 2007
Copyright @ 2007 RT Edwards Inc.Boiling heat transfer in small diameter tubes has been experimentally investigated using R134a as the working fluid. The heat transfer periments were conducted with two stainless steel tubes of internal diameter 4.26 mm ...
Huo, Y, Karayiannis, TG, Tian, S
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Relative Environmental, Economic, and Energy Performance Indicators of Fuel Compositions with Biomass

Applied Sciences, 2020
The present study deals with the experimental research findings for the characteristics of ignition (ignition delay times, minimum ignition temperature) and combustion (maximum combustion temperature, concentration of anthropogenic emission), as well as ...
Dmitrii Glushkov, Galina Nyashina, Valeriy Medvedev, Kseniya Vershinina   +3 more
doaj   +1 more source

A Study of Evaporation Heat Transfer Coefficient Correlations at Low Heat and Mass Fluxes for Pure Refrigerants and Refrigerant Mixtures [PDF]

, 1993
An average R12 refrigerant correlation has been developed for the mass flux range of 25-100 kg/m2-s and the heat flux range of 2-10 kW/m2. Refrigerant mixtures of 80% R22/lO% R141b and 65% R22/35% R123 have also been tested over asjrniJar range of ...
Newell, T.A., Smith, M.K., Wattelet, J.P.   +2 more
core  

An overview of recent applications of computational modelling in neonatology [PDF]

, 2010
This article has been made available through the Brunel Open Access Publishing Fund.This paper reviews some of our recent applications of Computational Fluid Dynamics (CFD) to model heat and mass transfer problems in neonatology and investigates the ...
Fic, AM, Ginalski, MK, Ingham, DB, Nowak, AJ, Wrobel, LC   +4 more
core   +2 more sources

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Mathematical modeling of the electric spark ignition of the coal-water particle fuel under conditions relevant to the internal combustion engines

MATEC Web of Conferences, 2017
The results of the mathematical simulation of the coal-water fuel particle in the conditions of electric-spark discharge have been given.
Syrodoy Samen, Penyazkov Oleg, Assad Mohamad, Gutareva Nadegda   +3 more
doaj   +1 more source

Heat transfer in the vortex zone of a cyclone-bed chamber of furnace unit with fluidized bed

Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2019
An experimental investigation of the heat-transfer coefficient to a spherical probe in a cyclone-bed chamber with fluidized bed in the “cold” and “hot” regimes has been carried out.
E. A. Pitsuha, E. K. Buchilko, Yu. S. Teplitskii, D. S. Slizhuk   +3 more
doaj   +1 more source

Effect of Thermal Conductivity and Emissivity of Solid Walls on Time-Dependent Turbulent Conjugate Convective-Radiative Heat Transfer [PDF]

Journal of Applied and Computational Mechanics, 2019
In the present study, the conjugate turbulent free convection with the thermal surface radiation in a rectangular enclosure bounded by walls with different thermophysical characteristics in the presence of a local heater is numerically studied.
Igor V. Miroshnichenko, Mikhail A. Sheremet   +1 more
doaj   +1 more source