Results 71 to 80 of about 797,009 (296)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Variational Characterizations of Local Entropy and Heat Regularization in Deep Learning
, 2019 The aim of this paper is to provide new theoretical and computational understanding on two loss regularizations employed in deep learning, known as local entropy and heat regularization.
Kaplan, Zach +2 more
core +1 more source
Sensitivity of the Heat-Transfer Coefficient Calculation [PDF]
Materials Performance and Characterization, 2014 AbstractThe purpose of the Liščić/Petrofer probe is to determine the cooling intensity during liquid quenching in laboratory and workshop environments. The surface heat-transfer coefficient is calculated by the one-dimensional finite-volume method from the smoothed temperature curve, measured at a near-surface point in the probe.
openaire +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Teshugang, 2011 Based on data of 150 t converter steelmaking at Anyang Steel, the calculation of charging material balance and heat balance have been carried out and a calculation model is established.
吕亚 +5 more
doaj
Smeared heat-kernel coefficients on the ball and generalized cone
, 1998 We consider smeared zeta functions and heat-kernel coefficients on the bounded, generalized cone in arbitrary dimensions. The specific case of a ball is analysed in detail and used to restrict the form of the heat-kernel coefficients $A_n$ on smooth ...
Avramidi I. +15 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
BuildingsIn view of the problem that the exchange effectiveness is calculated according to a fixed value or only considering the influence of outdoor air parameters when analyzing the suitability of total heat recovery for plate heat recovery equipment in air ...
Ming Dong +4 more
doaj +1 more source
MATEC Web of Conferences, 2018 The aim of the work is to improve the energy efficiency of heating boiler plants by reducing the spe-cific electric energy consumption for heat supply by using the variable-frequency drive (VFD) with different methods of heat supply regulation. Hydraulic
Pyatin Andrey +2 more
doaj +1 more source
Calculation of Heat-Kernel Coefficients and Usage of Computer Algebra
, 1995 The calculation of heat-kernel coefficients with the classical DeWitt algorithm has been discussed. We present the explicit form of the coefficients up to $h_5$ in the general case and up to $h_7^{min}$ for the minimal parts.
A. Schaale +28 more
core +1 more source