Results 51 to 60 of about 350,035 (281)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Heat Transfer in Semitransparent Medium Caused by Laser Pulse

International Journal of Industrial Engineering and Production Research, 2008
In this paper, the combination of conduction with radiation into a semitransparent medium which includes absorption, emission and scattering has been investigated.
E . Izadpanah, A . Akhavan Taheri, M . H Hekmat, S . Talebi   +3 more
doaj  

Effect of electrically aligned polycrystalline diamond flakes on the through-plane thermal conductivity of heat conduction sheets

Functional Diamond
Heat conduction sheets, which are composed of a thermally conductive filler and a base elastomer matrix, are important for dissipating heat from devices to a heat sink.
Masafumi Inaba, Seiya Seike, Yingchen Chen, Soichiro Ichiki, Yoshihiko Kubota, Shinya Ohmagari, Michihiko Nakano, Junya Suehiro   +7 more
doaj   +1 more source

Weak coupling limits in a stochastic model of heat conduction [PDF]

, 2011
We study the Brownian momentum process, a model of heat conduction, weakly coupled to heat baths. In two different settings of weak coupling to the heat baths, we study the non-equilibrium steady state and its proximity to the local equilibrium measure ...
Redig, Frank, Vafayi, Kiamars
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Explicit Time Integration Method Based on Uniform Trigonometric B-Spline Function for Transient Heat Conduction Analysis

Applied Sciences
In this paper, a new explicit time integration method for transient heat conduction analysis is proposed based on the uniform trigonometric B-spline function. The algorithmic calculation procedure for solving the heat conduction problem is given.
Zixu Li, Yongyu Hong, Pan Wang, Weibin Wen   +3 more
doaj   +1 more source

Barycentric Rational Collocation Method for Nonlinear Heat Conduction Equation

Journal of Applied Mathematics, 2022
Nonlinear heat equation solved by the barycentric rational collocation method (BRCM) is presented. Direct linearization method and Newton linearization method are presented to transform the nonlinear heat conduction equation into linear equations.
Jin Li
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Universal Heat Conduction in YBa_2Cu_3O_6.9

, 1997
The thermal conductivity of YBa_2Cu_3O_6.9 was measured at low temperatures in untwinned single crystals with concentrations of Zn impurities from 0 to 3% of Cu.
Benoit Lussier, Ctirad Uher, D. A. Bonn, D. N. Basov, Hervé Aubin, I. Maggio-Aprile, J. Dominec, Kamran Behnia, Kathryn A. Moler, Kuan Zhang, Louis Taillefer, M. J. Graf, M. R. Norman, P. A. Lee, P. D. Thacher, P. Hirschfeld, P. J. Hirschfeld, R. A. Fisher, Robert Gagnon, Robert Gagnon, Robert Gagnon, S. Schmitt-Rink, S. Shamoto, Y. Fukuzumi, Y. Sun, Y. Sun   +25 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source