Results 101 to 110 of about 3,389,680 (300)
, 2001 If not designed and installed properly in a suitable location, heat pumps can produce noise at nuisance levels for adjacent residents. Various (national and international) systems and guidelines used for measuring, predicting and regulating noise levels ...
Eggenschwiler, Kurt (author) +1 more
core +1 more source
The design of mini/micro heat exchangers: A world of opportunities and constraints [PDF]
, 2018 Micro heat exchangers and heat sinks broadened their use in many technological fields during the last two decades. The reduction of the dimensions of the channels allows to obtain ultra-compact heat exchangers characterized by higher surface-to-volume ...
Gian Luca Morini +5 more
core +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Pattern recognition residential demand response: An option for critical peak demand reduction [PDF]
, 2010 Influencing households to adopt sustainable energy consumption behaviour is important to the transition towards a sustainable energy future. However, if one aims at influencing the energy consumption habits of people, one should also be able to estimate ...
Krumdieck, S., Gyamfi, S., Brackney, L.
core
EnergiesSpace and water heating for residential and commercial buildings amount to a third of the European Union’s total final energy consumption. Approximately 75% of the primary energy is still produced by burning fossil fuels, leading to high greenhouse gas ...
Alexander Jüstel +5 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
The potential for bioenergy crops to contribute to meeting GB heat and electricity demands [PDF]
, 2014 The paper presents a model system, which consists of a partial equilibrium model and process-based terrestrial biogeochemistry models, to determine the optimal distributions of both Miscanthus (Miscanthus × giganteus) and short rotation coppice willow ...
Tallis, M.J. +44 more
core +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source